The LSU Tigers head to Chestnut Hill to face the Boston College Eagles on Wednesday night as part of the ACC/SEC Challenge. The Tigers are looking to keep their undefeated season alive in the early going, while Boston College enters at 4-4 and is ranked last in the ACC in scoring. But with the Eagles playing at home and hoping to rise to the occasion, the Eagles will still hope to pull off an upset here. Before tip, continue reading to get my LSU vs Boston College prediction.
Our LSU vs Boston College Pick
- Pick: LSU -7.5
- Confidence: ★★★★☆


Game Snapshot
- Matchup: LSU Tigers @ Boston College Eagles
- Date & Time: December 3, 2025, 7:15 p.m. ET
- Venue: Silvio O. Conte Forum, Boston, Massachusetts
- Broadcast: ACC Network
LSU vs Boston College Odds
| Spread | Moneyline | Total |
|---|---|---|
| LSU −7.5 | LSU −325 / Boston College +260 | 147.5 |
Key Storylines
- LSU enters this game undefeated at 7-0, coming off a dominant 96–63 win over DePaul in the Emerald Coast Classic. The Tigers shot a blistering 68.6% from the floor in that game, with seven players scoring in double digits. That victory capped a neutral-site tournament where they looked balanced and efficient on both ends throughout.
- The offense for LSU has been explosive. They rank among the national leaders, averaging 94.3 points per game. Their two leading contributors are 6-foot-10 forward Michael Nwoko at 17.4 PPG and guard Dedan Thomas Jr. at 14.4 PPG. Thomas is also handing out 7.0 assists per game. The Tigers’ offensive depth and balance makes them difficult to slow down.
- Boston College is hoping to use their home-court advantage to stay competitive in this game. The Eagles just snapped a short slump with a 73–60 win over Harvard, showing signs of life offensively with a season-high 12 made threes. The Eagles got a spark from freshman Caleb Steger, who hit three threes in a three-minute stretch in the second half. If Steger, leading scorer Donald Hand Jr. (15.4 PPG), and Fred Payne (12.9 PPG) can all contribute, the Eagles might keep this game within reach.
- Defensively, Boston College isn’t terrible. They allow 65.6 points per game, which is respectable. Their challenge will be defending the glass, as LSU rebounds well and has a big in Nwoko who has dominated the paint so far this year. For the Eagles to have a chance, they’ll need energy on the boards from forwards like Aidan Shaw, who averages 8.9 rebounds per game.
- The fact that this is the first-ever meeting between these two programs adds an element of unpredictability to the proceedings. It will be interesting to see how both teams approach one another in this unfamiliar situation.
Betting Trends
- Boston College is 3-5 against the spread so far this season.
- LSU is 4-3 on the year so far in the point spread market.
- LSU is 5-2 to the over through seven games.
- The under has hit 5 times in 8 games for the Eagles.
LSU vs Boston College Model Projection
Score Projection: LSU 87 – Boston College 76
Win Probability: LSU 82%, Boston College 18%
Final Thoughts
LSU should be able to create enough separation to cover the spread on the road against Boston College in this contest. The Tigers have the edge in the paint and on the glass and that should translate to more second-chance buckets and points at the rim.

