Portland Trail Blazers vs Cleveland Cavaliers Prediction - 12/3/2025

Updated December 3, 2025


Updated December 3, 2025

The Portland Trail Blazers head to Cleveland tonight to take on the Cleveland Cavaliers on Wednesday night. This is a clash that pits a young Blazers squad licking its wounds against a Cavs team seeking stability despite a ton of injuries. Here, I break down this inter-conference matchup in the NBA and provide you with my Trail Blazers vs Cavaliers prediction for Wednesday night's game.
Pick: Cleveland Cavaliers -9.5
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Spread | Moneyline | Total |
|---|---|---|
CLE –9.5 | CLE –450 / POR +370 | 240.5 pts |
Player | Prop |
|---|---|
Donovan Mitchell | Over 28.5 points |
Evan Mobley | Over 10.5 rebounds |
Shaedon Sharpe | Under 19.5 points |
Score Projection: Portland 108 – Cleveland 122
Win Probability: Portland 28%, Cleveland 72%
Both of these teams are depleted from a health standpoint going into this game. But the Cavs do have a rest advantage going into this matchup thanks to the Blazers playing last night. I think that will help the Cavs win this game convincingly on Wednesday night and I am going to lay the points with Portland in what should be an interesting matchup between two teams trying to figure things out in spite of a ton of adversity.
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