The Los Angeles Chargers and Arizona Cardinals both enter Week 12 having played night games in Week 11. Here, they face one another on shorter rest than usual, in a game that both teams need if they want to improve their playoff chances. In our NFL betting picks for Sunday afternoon, we take a closer look at Chargers vs Cardinals from Glendale.
Chargers vs Cardinals Betting Pick
|ℹ️ The Pick:||Chargers -3.5|
|🎁 Recommended Sportsbook Promo:||Risk-Free Bet at Unibet|
|🏈 Promo Code:||NONE NEEDED|
This game will be played at State Farm Stadium at 4:05 PM ET on Sunday, November 27, 2022.
Why Bet The Chargers:
✅ Arizona is coming off of a short week and international travel ahead of this game, having played in Mexico City on Monday Night Football in Week 11.
✅ The Cardinals are still dealing with injury uncertainty at the quarterback position. Kyler Murray has missed the last two games due to injury and is no guarantee to play in this game, or to be fully healthy if he does.
✅ The Chargers are the second best team in the NFL against the spread this year. They are 7-3 against the spread, and will continue to dominate against the number here.
Los Angeles Chargers
Team Advanced Defense
|Austin Johnson||DL||Knee (mcl)||Out||11/26/22|
|Donald Parham Jr.||TE||Concussion||Out||11/26/22|
|Jalen Guyton||WR||Knee (acl)||Out||11/26/22|
|Kenneth Murray Jr.||LB||Neck||Probable||11/24/22|
|Trey Pipkins III||OT||Knee||Probable||11/24/22|
|Byron Murphy Jr.||CB||Back||Out||11/26/22|
|Justin Pugh||OL||Knee (acl)||Out||11/26/22|
|23||Avg Opp Score||28.67|
|22.33||Avg Opp Score||34.33|
|24.4||Avg Opp Score||30.8|
|23.6||Avg Opp Score||28.6|
|25.8||Avg Opp Score||25.2|
|26.8||Avg Opp Score||31.1|
Head to Head
Teams Last 10
Best Chargers vs Cardinals Sportsbook Promo
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Los Angeles Chargers
On Sunday Night Football in Week 11, the Los Angeles Chargers were beaten in primetime by the Kansas City Chiefs. That was the second time this season that they lost a night game to the Chiefs, and the Chargers are all but out of the AFC West race as a result. Now, the Chargers have to focus on compiling wins to help their chances in the Wild Card chase.
For this game, the Chargers have to stop the pass in a way they could not against the Chiefs. But the Cardinals have fewer elite weapons than the Chiefs, and there is nobody like Travis Kelce on their roster. Still, the threat of DeAndre Hopkins will make this game a tall task for the Chargers defensively.
The Arizona Cardinals come into this game coming off of a short week, having played the San Francisco 49ers in Mexico City. Just as important as their rest schedule is their health at the quarterback position. That area is in complete question coming into this game, as the status of Kyler Murray is uncertain coming into this inter-conference contest.
If Murray is unable to go again, the Cardinals will have trouble dealing with the pass rush of the Chargers. Murray’s mobility would give them a much better chance of escaping the pressure from the Chargers defensive line. If Colt McCoy starts for a third straight week, that mobility will be gone, and the Cardinals’ chance of winning could be gone with it.