Who: Clemson at Louisville
Time: November 6, 2021 7:30 EST
Venue: Cardinal Stadium – Louisville, KY
Clemson at Louisville Odds:
All College Football betting lines, odds and prop bets are available on Caesars Sportsbook.
Moneyline: Clemson -178 | Louisville +142
Spread: Clemson -3.5 (-102) | Louisville +3.5 (-120)
Total: Under 45.5 (-114) | Over 45.5 (-106)
Clemson at Louisville Betting Preview
An ACC showdown is set for Saturday, November 6, 2021, when the Clemson Tigers (5-3, 4-2) visit the Louisville Cardinals (4-4, 2-3). Clemson is third in the ACC Atlantic and trail Wake Forest by 3.5 games. Louisville is in fourth and cannot win the Atlantic division. This game will air live on the ACC Network.
Through eight games, the Clemson offense is averaging 21.3 points per game and 328.3 yards per game, 177.8 through the air and 150.5 on the ground. Defensively, the Tigers are allowing just 15.3 points and 324.1 yards, 211.0 passing and 113.1 rushing.
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The Louisville offense is averaging 29.4 points per game and 448.1 yards per game, 245.4 through the air and 202.8 on the ground. Defensively, the Cardinals are allowing 27.1 points and 415.4 yards, 281.4 passing and 134.0 rushing.
Below is my pick, and preview, for the battle between the Clemson Tigers and Louisville Cardinals.
Clemson at Louisville Betting Stats
Clemson
- Clemson are 1-8 ATS in their last 9 games.
- The total has gone UNDER in 6 of Clemson’s last 8 games.
- Clemson are 15-5 SU in their last 20 games.
- Clemson are 4-1 ATS in their last 5 games against Louisville.
- Clemson are 6-0 SU in their last 6 games against Louisville.
- Clemson are 15-3 SU in their last 18 games on the road.
- Clemson are 1-7 ATS in their last 8 games this season.
- Clemson are 17-3 SU in their last 20 games against an opponent in the Atlantic Coast conference.
- Clemson are 1-6 ATS in their last 7 games against an opponent in the Atlantic Division division.
- The total has gone OVER in 5 of Clemson’s last 7 games played in November.
Louisville
- Louisville are 4-2 ATS in their last 6 games.
- The total has gone UNDER in 4 of Louisville’s last 5 games.
- Louisville are 5-1 SU in their last 6 games at home.
- The total has gone UNDER in 6 of Louisville’s last 8 games this season.
- The total has gone UNDER in 4 of Louisville’s last 5 games against an opponent in the Atlantic Coast conference.
- Louisville are 4-1 ATS in their last 5 games against an opponent in the Atlantic Division division.
- Louisville are 3-8 ATS in their last 11 games played in November.
- Louisville are 13-4 SU in their last 17 games played in week 10.
Clemson at Louisville Pick
Last time out, Clemson hosted the Florida State Seminoles and came away with a 30-20 win. This is one of the greatest backdoor covers ever as Clemson fell into the end zone after Florida State attempted several laterals down three as the game expired. D.J. Uiagalelei went 19/31 for 189 yards, one touchdown, and one interception on the day. Will Shipley was a monster on the ground as he rushed the ball 25 times for 128 yards, a 5.1 average, and two touchdowns. Defensively, the Tigers allowed 241 total yards and recovered two Florida State fumbles.
Louisville visited teh NC State Wolfpack and suffered a 28-13 defeat. This score is not indicative of how close this game was as Louisville was down one point with less than six minutes remaining. Malik Cunningham went 11/28 for 219 yards, one touchdown, one interception, and led the team with 76 rushing yards. Defensively, the Cardinals allowed 361 total yards and did not force any NC State turnovers.
Clemson vs Louisville Series History: Clemson has won all six meetings between these two schools.