In our MLB predictions for Tuesday, June 21, we are breaking down the opener of a three-game AL Central series from Target Field in Minneapolis to bring you the best Guardians vs Twins betting pick and odds. Cleveland meets Minnesota for the second time this season, and the Twins beat the Guardians 2-1 in a three-game set at Target Field in May. The visitors will give Aaron Civale a nod, while the hosts will counter with Joe Ryan.
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Guardians vs Twins Betting Pick
This game will be played at Target Field at 7:40 PM ET on Tuesday, June 21, 2022.
Why Bet The Twins:
✅ Aaron Civale (thigh) completed his rehab assignment and returns to a miserable 7.84 ERA and 1.52 WHIP. The 27-year-old right-hander has struggled mightily through his first seven starts (31 innings pitched) in 2022. Civale has yielded six earned runs in three of his previous five appearances.
✅ The Twins are more dangerous when hitting the righties. They own a 99 OPS+ against the lefties and a 113 OPS+ against the right-handed pitchers in 2022. Some of the current Twins have a strong record versus Aaron Civale. Byron Buxton is 3-for-10 with a couple of home runs; Max Kepler is 5-for-15 with a pair of doubles, while Gary Sanchez is 3-for-6 with a double and RBI against Civale.
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✅ Joe Ryan will meet the Guardians for the second time this term. The 26-year-old righty emerged victorious in a 3-1 win to Cleveland on May 15, throwing six innings of a one-run, four-hit ball. Ryan holds a 5-3 record with a strong 2.81 ERA and 1.02 WHIP in nine starts (48 IP) in 2022, and the current Guardians are slashing just .146/.157/.225 in 39 at-bats against him.
Cleveland Guardians
The Guardians have been on a tear over the last few weeks. They’ve won 15 of their previous 19 games overall and are undefeated in six consecutive series. The Guardians are now sitting at the second spot in the AL Central with a 34-28 record, only one game behind the Twins.
Cleveland has gone 13-4 through its first 17 outings in June. The Guardians’ pitching staff has registered a 2.94 ERA in that span, while their bullpen has amassed a 1.65 ERA, 3.51 FIP, and 11.2 K/9.
Minnesota Twins
The 38-30 Minnesota Twins are coming off a 7-1 defeat at the Arizona Diamondbacks last Sunday. It was their fourth loss in the last seven outings, and the Twins have scored only three runs over those four losing efforts.
Minnesota desperately needs more from its bullpen. The Twins’ relievers hold a 4.41 ERA, 4.53 FIP, and 1.43 HR/9 in 69.1 innings of work in June. Their offense has slashed a solid .260/.321/.442 so far this month.