The Jacksonville Jaguars head into Sunday’s AFC South matchup with the Tennessee Titans with momentum. They will try to keep that momentum going against the Titans, who are mired in a brutal season and are desperate for a spark. Before these division rivals do battle in Nashville, continue reading to find my Jaguars vs Titans prediction.
Our Jaguars vs Titans Pick
- Pick: Titans +5.5
- Confidence: ★★★★☆


Game Snapshot
- Matchup: Jacksonville Jaguars @ Tennessee Titans
- Date & Time: Sunday, November 30, 2025, 1:00 PM ET
- Venue: Nissan Stadium, Nashville, TN
- Broadcast: CBS
Jaguars vs Titans Odds
| Spread | Moneyline | Total |
|---|---|---|
| Jaguars –5.5 | Jaguars –270 / Titans +220 | Over/Under 41.5 |
Key Storylines
- The Jaguars are 7-4 and are battling for a playoff spot. They enter this week one game back of the Indianapolis Colts in the AFC South standings with two remaining games against the division-leading Colts. A win in Nashville would go a long way toward shoring up their postseason positioning.
- The Titans are 1-10 overall and 0-6 at home. They’ve dropped six straight games, but the last few losses have been close, including a 30-24 loss to the Seattle Seahawks last week. Tempered expectations won’t prevent the Titans from wanting to play well in a spot like this against a rival.
- This is a rivalry game. The rivalry between these teams has history, even if this season’s records make it lopsided on paper. For Jacksonville, this game is about consistency and not taking a matchup with a 1-10 team for granted. For Tennessee, the rest of the season is about pride and building toward the future.
Quarterback Play
Jacksonville will lean on Trevor Lawrence at quarterback. He enters the game with over 2,400 passing yards, 14 touchdowns, and 11 interceptions. Despite recent turnovers, including three picks last week, he remains capable of making plays under pressure.
On the Titans’ side, rookie Cam Ward has struggled for the most part. He’s thrown for over 2,200 yards this season, with 7 touchdowns and 6 interceptions. Tennessee needs Ward to avoid mistakes and get into a rhythm for the Titans to make a game of this.
Betting Trends
- Jacksonville is 6-5 against the spread this season.
- The Titans are 5-6 against the spread going into this week.
- The over has hit in 7 of their first 11 games.
- Jacksonville has gone over the total 6 times through 11 games.
Jaguars vs Titans Model Projection
Score Projection: Jaguars 24 – Titans 21
Win Probability: Jaguars 75%, Titans 25%
Final Thoughts
The Jaguars should be able to win this game against the struggling Titans. But I’ll take the points with Tennessee as a home underdog here. Tennessee has played three straight one-possession games and I’m expecting that trend to continue here in what should be a tight contest from Tennessee.

