The Los Angeles Rams will head to Charlotte to face the Carolina Panthers this Sunday in a big game for both clubs. With Los Angeles riding a long winning streak and Carolina fighting to keep its playoff hopes alive, this game will reveal a lot about the character of both teams. Before kickoff from Charlotte, you can continue reading to find my Rams vs Panthers prediction.
Our Rams vs Panthers Pick
- Pick: Panthers +10
- Confidence: ★★★★☆


Game Snapshot
- Matchup: Los Angeles Rams vs Carolina Panthers
- Date & Time: Sunday, November 30, 2025, 1:00 PM ET
- Venue: Bank of America Stadium, Charlotte, North Carolina
- Broadcast: FOX
Rams vs Panthers Odds
| Odds | Line |
|---|---|
| Spread | Rams −10 |
| Moneyline | Rams −700, Panthers +450 |
| Total | 44.5 |
Key Storylines
- The Rams arrive in Charlotte with momentum and a strong record. They have won six straight games and they will try to extend that streak here to move closer to locking up a playoff spot.
- The Panthers sit in the middle of the playoff picture and need a confident performance at home to keep their hopes intact. Carolina is 6-6 so far this season, which is a huge step forward from what we saw last year. But they will need to step up in a big way here to avoid dropping below the .500 mark.
Quarterback Play
The Rams are getting elite play from veteran passer Matthew Stafford. He has 2,830 passing yards, 30 touchdown passes, and just 2 interceptions on the year. Stafford is firmly in the NFL MVP conversation this year and he will try to move closer to earning that award with a strong performance that leads to a Rams win.
Carolina relies on Bryce Young to generate plays and keep drives alive from the quarterback position. He has shown flashes of elite play but also periods of inconsistency. Protection issues have led to a significant sack total. He is moving in the right direction when compared to previous years and this game is a huge test for Young against a quality opponent.
Betting Trends
- The Rams are 8-3 against the spread going into this contest.
- The Panthers have covered the spread in 7 of their first 12 games going into Sunday’s game.
- The under has hit in 7 of the Rams’ first 11 games.
- The Panthers have split their first 12 games in the over/under market, going 6-6 on their totals this season.
Rams vs Panthers Model Projection
Score Projection: Rams 24 – Panthers 17
Win Probability: Rams 87%, Panthers 13%
Final Thoughts
The Rams should be able to pick up the win on the road in this matchup and get to 10 wins on the season with five weeks to go. But I’m taking the points with the Panthers in this matchup. Carolina has won 3 of its 5 games at home this season and the Panthers should continue to hang tough on their home turf here.

