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Arizona Cardinals
San Francisco 49ers

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Arizona Cardinals vs San Francisco 49ers Prediction & Picks – 10/6/2024
Cardinals vs 49ers Betting Odds
Spread: | Arizona Cardinals 7.5, San Francisco 49ers -7.5 |
Over/Under: | 49.5 |
Moneyline: | Arizona Cardinals 285, San Francisco 49ers -345 |
Arizona Cardinals vs San Francisco 49ers Win Probabilities
Implied Win %: | Projected Win %: |
Arizona Cardinals - 25% | Arizona Cardinals - 17% |
San Francisco 49ers - 75% | San Francisco 49ers - 83% |
Implied Win % in sports betting represent the probability of an outcome as suggested by the betting odds. It's a way for bettors to gauge the likelihood of an event occurring based on the odds offered by sportsbooks.
Projected Win %, also known as projected win probability, is an estimate by ATS.io to determine the likelihood that a team will win a game or event. This projection is often based on various factors such as team performance, statistics, and historical data.
Arizona Cardinals vs San Francisco 49ers Betting Preview
The last time these two teams played each other was Week 15 in 2023. That game resulted in a win for the 49ers with a final score of 45-29. They say, good teams win, but great teams cover. The 49ers not only won, but covered the -12.0 spread that game. The Game Total for that game was 48.0 and which the Over hit.
Arizona's biggest weakness has been their defense, ranking #29 in the league while allowing 380 yards per game. Much of their struggle has come in trying to lock down the pass game, as they've allowed opposing QBs pass for the #9-most yards per game: 229. The Cardinals have been at their worst when it comes to shutting down opposing wide receivers, allowing them to complete 70.5% of their targets, #1-highest in football. Arizona's worst position group in coverage has been their linebackers, which rank just #28 in the league in locking down route-runners. Arizona's pass rush has been weak this year, being weighed down by their defensive ends, which check in as just the #32-best unit in terms of getting to the passer. This represents a particular disadvantage for Arizona given that the 49ers have excelled in the pass game this year, accumulating 9.2 yards per target (#1-best in the league). In terms of their offense, the Cardinals have ranked #18 in the league in total yards per game. They've passed for 188 yards per game (#21 in football). On the ground they've ranked #13 with 4.45 yards per carry.
San Francisco's primary advantage has been their offense, which ranks #1 in the NFL at 405 yards per game. The quality of their passing attack has led to much of their success. The 49ers 280 yards per game through the air ranks #1-best in football this year. They haven’t made things easy for opposing defense given they they've also positioned themselves in the top 10 on the ground as well, rushing for 5.1 yards per carry. When it comes to their defense, the 49ers check in at #14 in football when it comes to total yards allowed per game. Opposing air attacks have notched 227 yards per game against San Francisco this year (#11 in football). Opposing ball-carriers have ranked #25 against them with 4.16 yards per ground attempt. This 49ers defense hits their peak effectiveness when it comes to defending opposing tight ends, keeping them in check at just 6.48 yards per target (#1-best in the league). San Francisco's defensive effectiveness in the pass game bottoms out when it comes to defending opposing running backs, who have scorched them for 47 yards per game (#4-worst in the league).
Arizona Cardinals vs San Francisco 49ers Prediction
Final Score: Arizona Cardinals 19.38 vs San Francisco 49ers 30.74
**NOTE: The above stats and rankings are adjusted for context based on sample size and matchup factors. Note that, by design, these stats will not match up with those you find on stat pages and leaderboards around the industry, however are more predictive for ranking stats and for contextualizing the data. Statistics include data from the beginning of the 2023 NFL season to the present time in the 2024 season to allow a more representative sample size.
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