The Vanderbilt Commodores (9‑2) hit the road to face the Tennessee Volunteers (8‑3) at Neyland Stadium in a showdown that could have major postseason implications for Vanderbilt. Both teams enter ranked in the top 20, and both are aware that this rivalry game carries extra weight this season with everything on the line. Before kickoff from Knoxville, continue reading to find my Vanderbilt vs Tennessee prediction for Saturday afternoon.
Our Vanderbilt vs Tennessee Pick
Pick: Tennessee -2.5
Confidence: ★★★★☆


Game Snapshot
- Matchup: Vanderbilt Commodores vs Tennessee Volunteers
- Date & Time: Saturday, November 29, 2025, 3:30 PM ET
- Venue: Neyland Stadium, Knoxville, Tennessee
- Broadcast: ESPN
Key Storylines
- Vanderbilt’s playoff hopes: The Commodores arrive with a 9‑2 record, and a win here would vault them into double‑digit wins for a program that historically has seldom reached that milestone. Their head coach recently received a contract extension, a vote of confidence that underscores the seriousness with which Vanderbilt has treated this season. The pressure to capitalize on this moment is real and the Commodores could really use a win here to make an argument for a playoff spot.
- Rivalry status and stakes for Tennessee: Tennessee has won the last six games in the series and holds a huge edge all-time. They’re motivated to protect their home turf, secure a ninth win, and solidify their bowl positioning.
- Offensive firepower on both sides: Both offenses rank among the nation’s best offensively. The potential for a high-scoring game is strong, especially given some defensive vulnerabilities on both rosters. Add the emotion, rivalry, and playoff implications into the mix, and you have the recipe for a shootout full of big plays and momentum swings.
Quarterback Play
On one sideline, Vanderbilt’s Diego Pavia has carried the Commodores with an efficient, high‑volume passing attack. He enters the game with 2,924 passing yards, 26 touchdowns, and 6 interceptions, with a completion rate near 72%. Pavia also has over 660 rushing yards and 8 rushing touchdowns.
Tennessee’s quarterback is Joey Aguilar, who has completed 67% of his passes for 3,145 yards, 23 touchdowns, and 10 interceptions this season. The battle between Pavia’s explosiveness and Aguilar’s steadiness will be central to deciding the game’s flow.
Betting Trends & H2H
- Tennessee leads the all-time series convincingly and has won the last six games between the schools.
- Vanderbilt enters 5‑0 against the spread (ATS) in its last five games, and 7‑1 ATS in its last 8 road games overall.
- Tennessee is 4‑6-0 ATS this season, and only 3‑4 ATS when favored by four points or more.
- The total has gone over in 4 of Vanderbilt’s last 5 games.
Vanderbilt vs Tennessee Model Projection
Score Projection: Tennessee 34 – Vanderbilt 31
Win Probability: Tennessee: 58%, Vanderbilt: 42%
Final Thoughts
I am going to lay the points with Tennessee in this contest from Knoxville. Pavia should have another big game for the Commodores, but I don’t think that the defense of Vandy will hold up well enough to win this game and keep their playoff hopes alive. This game will be incredibly exciting, but I’ll give the Vols the nod in the end.

