Both the San Francisco 49ers and Tampa Bay Buccaneers have been fixtures in the playoffs in the NFC in recent years. On Sunday, they will do battle in Week 10 of the regular season, with both teams looking to notch an important win for their playoff hopes. San Francisco is a 5.5-point road favorite ahead of this one, while the total stands at 48.5. In our preview of 49ers vs Buccaneers, we break down this NFC showdown and give you our NFL picks for the game.
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49ers Coming Off Bye Week
The San Francisco 49ers were inactive last week, having their bye week in Week 9. Before that, the Niners beat up on the Dallas Cowboys on Sunday Night Football in Week 8, with the return of Deebo Samuel from pneumonia giving their offense a major spark. This week, the Niners will look to use Samuel and the rest of their weapons to punish a Buccaneers team that has struggled on defense against quality offenses like the Ravens and Falcons previously this year.
Bucs Facing Short Rest Week
While the 49ers are coming off of their bye week and getting extra rest before this game, the Tampa Bay Buccaneers are dealing with short rest going into this matchup. That is a product of Tampa Bay playing on Monday Night Football in Week 9 against the Kansas City Chiefs in a brutal bit of scheduling for Baker Mayfield and the Bucs. Still, there are no excuses in the NFL, and the Buccaneers will need to find a way to overcome their schedule to get a win at home in this matchup.
49ers vs Buccaneers Prediction
Tampa Bay is at home for this 49ers vs Buccaneers matchup in the NFC. But the Bucs are disadvantaged in several areas beyond where this game is being played. Tampa is at a huge rest disadvantage in this contest, not to mention the Niners having the talent edge here. Look for the 49ers to come off of their bye and cover the spread as a road favorite at Raymond James Stadium.