Quarterback stability, or a lack thereof, has been a major storyline for both the Buffalo Bills and Indianapolis Colts so far this season. On Sunday, the Bills and Colts will square off in Week 10 action, with Buffalo looking to punish Indianapolis for their lack of stability at the most important position on the field. Buffalo is a four-point favorite going into this contest, with the total standing at 47.5 points. Continue reading for our analysis and our NFL betting picks for Bills vs Colts from Indianapolis.
Bet $5, Get $200 in Bonus Bets Instantly + King of the Court
21+ to wager. Please Gamble Responsibly. Gambling Problem? Call 1-800-NEXT-STEP
Promo Code: Click To Claim
Bills Looking For Fifth Straight Victory
The Buffalo Bills are one of the hottest teams in the NFL going into Week 10 of the regular season. They have won four games in a row, including a division game in Week 9 over the Miami Dolphins, which they won with a late 61-yard field goal from Tyler Bass. The fact that the Bills struggled defensively against Miami is a concern going into this game, but there are very few defenses that have an easy time against a healthy Miami offense, to be fair.
Can QB Change Help Colts Overcome Buffalo?
The Indianapolis Colts have made the decision to bench second-year quarterback Anthony Richardson, who has had issues with both effectiveness and his physical fitness on the field of late. Instead, Joe Flacco will be the starting quarterback for Indianapolis until further notice. Flacco has been more effective than Richardson in limited action this season, but that might not remain the case against an elite Bills team.
Bills vs Colts Betting Prediction
We will lay the points with Buffalo in this Bills vs Colts matchup. Flacco has played well so far this season, but too much of his action in 2024 has come against bad AFC South competition for us to be convinced he is the real deal. Look for Josh Allen and company to outclass the Colts offense and to get their fifth straight win in this AFC showdown.