The final game of the 2024-25 women’s college basketball season will pit a legendary program against a current dynasty in the sport. The UConn Huskies will take on the South Carolina Gamecocks on Sunday, April 6, 2025 in Tampa, FL with the national championship on the line. With both teams winning by double-digits in the Final Four, this UConn vs South Carolina matchup is everything we could have asked for to close out this season.
At Caesars Sportsbook, UConn enters this matchup as a 5.5-point favorite. The over/under for this championship game has been set at 131.5. Here, we break down this national championship showdown as UConn and South Carolina look to add to their collection of national championship trophies in women’s college basketball.
UConn One Win From 12th Championship
The UConn Huskies were the two-seed in their region of the 2025 March Madness bracket in women’s basketball. But they were never challenged leading into the national title game, taking advantage of the injury to USC’s Juju Watkins in the Elite 8 while playing some spectacular basketball of their own to reach this stage. After dismantling UCLA in the national semifinals on Friday, UConn looks like a legitimate threat to win their 12th title in program history.
Paige Bueckers is the star of this UConn team, as she is expected to go first overall in this year’s WNBA Draft. But success in this game will come down to how Azzi Fudd and Sarah Strong shoot the basketball. They were both efficient against UCLA and another strong performance from both players could be enough to help UConn take down the Gamecocks.
South Carolina On Cusp Of Third Title In Four Years
Dawn Staley has led the South Carolina Gamecocks to two championships in the last three seasons. Now the Gamecocks are one win away from getting a third title in four years if they can hold serve as the one-seed going into this national championship game. South Carolina beat Texas 74-57 in their national semifinal on Friday, holding Texas to just 22 points in the final 20 minutes of action. The defense for Staley’s team will be the determining factor in this matchup with UConn.
South Carolina only attempted 11 three-point shots against Texas in the Final Four. But they made seven of those outside shots, with Te-Hina Paopao making three of her four attempts from the outside. How efficient the Gamecocks are from the perimeter in this game will be something to monitor, while they continue to try to wear opponents down with their physicality inside the arc at the same time.
During the regular season, UConn demolished South Carolina by a score of 87-58 on the Gamecocks’ home floor. South Carolina shot just 3-17 from three-point range in that contest and were held to just 23 first-half points. Needless to say, South Carolina will need to be better in this game to win it and UConn will expect better from their opponents here.
UConn vs South Carolina Prediction

South Carolina +5.5 (-110) over UConn
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- We expect better three-point shooting from South Carolina than we saw in their first matchup with UConn this season.
- South Carolina is built to wear teams down in the second half and we expect them to do that again in this marquee matchup.