The Oregon Ducks and Arizona Wildcats will do battle in the second round of the 2025 NCAA Tournament on Sunday, March 23, 2025. This game features former Pac-12 rivals who have since joined other leagues. The Oregon vs Arizona rivalry will be renewed for one night with a place in the Sweet 16 hanging in the balance.
Looking at the latest odds from bet365, Arizona is a 5.5-point favorite going into this game. They have made the total for the contest 153.5. Here, you will find our analysis for this NCAA Tournament matchup and get our prediction for a game where both teams will want to cost their rival a place in the next round.
Oregon Enters Off Dominant Performance
The Oregon Ducks looked spectacular in the opening round of this year’s NCAA Tournament. Oregon beat Liberty convincingly, taking a 24-point halftime lead and never looking back. Here, the Ducks will look to grab another victory, though it is not expected that they will get off to quite as strong a start as they did against the Flames on Friday.
Oregon’s Jackson Shelstad will be key to Oregon’s success against Arizona on Sunday. He made six of his eight shots in the first half in Friday’s win, with his efficiency helping the Ducks to put some distance between themselves and the Flames. Another efficient showing from Shelstad could allow them to earn a trip to the Sweet 16 in the East Region.
Arizona Set For Duck Hunt In Seattle
The Arizona Wildcats also dominated their first-round opponent in this year’s NCAA Tournament. They beat up on the Akron Zips in the opening round, winning by 28 points to make it to round two. The Wildcats shot 48% from three-point range in that contest and will look to punish another opponent from three-point range in this game.
Limiting turnovers will be key for the Wildcats if they want to win this game and advance to the next weekend of tournament action. They turned the ball over 16 times against Akron, with their starters contributing nine of those turnovers. While Arizona was able to get away with turning the ball over against Akron, they may not have the same luxury against an opponent from the Big Ten who is very familiar with them.
Oregon vs Arizona Prediction

Arizona -5.5 (-110) over Oregon
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- Arizona shouldn’t be caught off-guard by Oregon given their familiarity with each other as former conference rivals.
- Arizona has a big edge offensively according to Kenpom’s ratings and we tend to agree.