The Philadelphia Flyers head into Wednesday’s road game against the Florida Panthers expecting a tough challenge. The Panthers are back‑to‑back defending champions and are home‑favorites at Amerant Bank Arena. Philly will try to avoid a second straight loss on the road in Florida in this matchup. Before the opening face-off in Florida, keep reading to find my Flyers vs Panthers prediction for this contest.
Our Flyers vs Panthers Pick
- Pick: Panthers moneyline
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Philadelphia Flyers vs Florida Panthers
- Date & Time: Wednesday, November 26, 2025, 7:00 PM ET
- Venue: Amerant Bank Arena, Sunrise, Florida
- Broadcast: ESPN+
Key Storylines
Recent form
The Panthers arrive back home having won 5 of their last 7 games, including a commanding 8–3 triumph over the Nashville Predators on Monday. In that game, 12 different skaters registered points and their backup netminder made 36 saves. Florida appears to be settling in just as they begin a long homestand. The Flyers are 11–7–3 on the season and have shown signs of life on the road. Over their last 10 games, they’ve gone 5–3–2 and they will try to find a way to win on the road against the defending champs.
Goaltending
Goaltending will likely be a major area of focus. The Flyers appear to have the edge in goaltender save percentage and reliability with Dan Vladar in goal. But the gap between Vladar’s numbers this year and those of Florida’s Sergei Bobrovsky isn’t massive by any means and it will take a strong individual effort from one of the two netminders to win this game.
Key skaters
The Panthers lean heavily on Brad Marchand, who leads the squad with 13 goals and 12 assists for 25 points. Winger Sam Reinhart (13 goals, 8 assists) also remains a dangerous threat every time he touches the puck. Philadelphia’s Trevor Zegras (7 goals, 14 assists) and Travis Konecny (5 goals, 12 assists) are their top offensive weapons. Philadelphia’s strength continues to be their collective defensive effort, not individual offensive fireworks, but those two skaters will be important here.
Best Player Props
| Player | Prop |
|---|---|
| Sam Reinhart | Over 0.5 Goals |
| Trevor Zegras | Over 1.5 Shots on Goal |
| Travis Konecny | Over 0.5 Points |
Betting Trends & H2H
- The Flyers and Panthers have split their first two regular-season meetings.
- The home team has won each of the first two games between these squads.
- The Flyers are 12-9 on the puckline heading into this matchup.
- The under is 12-10 in games involving the Flyers this season.
- Florida is 7-15 on the puckline heading into this contest.
- The Flyers are 11-11 in the over/under market this year.
Flyers vs Panthers Model Projection
Score Projection: Panthers 4 – Flyers 2
Win Probability: Panthers 62%, Flyers 38%
Final Thoughts
Florida should have no problem winning this game at home. The Panthers are trending in the right direction and they should continue to do so as their roster continues to get healthier. I’ll take the Panthers on the moneyline, though I don’t mind the idea of backing the Panthers to cover the puckline at a much better price.
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