The Cleveland Cavaliers and Miami Heat will meet on Wednesday in what promises to be an interesting contest in the Eastern Conference. Both teams sit at 7‑4 heading into Wednesday’s game, but differences in roster health are set to drastically alter the betting landscape for this matchup. I break down those injury issues and everything else you need to know below and give you my Cavaliers vs Heat prediction.
Our Cavaliers vs Heat Pick
Pick: Miami Heat ‑5.5
Confidence: ★★★★☆
Game Snapshot
- Matchup: Cleveland Cavaliers @ Miami Heat
- Date & Time: Wednesday, November 12 , 2025, 7:30 p.m. ET
- Venue: Kaseya Center, Miami, Florida
- Broadcast: NBA League Pass
Key Storylines
One of the most crucial storylines going into this game is roster availability. Cleveland appears to be facing significant absences. Key players like Donovan Mitchell, Evan Mobley, and Darius Garland are all listed as out for this contest. Miami is missing Bam Adebayo (toe) and Tyler Herro (foot). Both teams will have to overcome adversity if they want any shot at winning this game in South Florida.
Miami is riding a three‑game winning streak and enjoys a perfect 5‑0 record at home this season. Cleveland is just 3‑3 on the road and has shown cracks when forced to play without its top contributors. Miami leads the league in scoring at 125.5 points per game, while Cleveland’s scoring has dipped when playing outside of Northeast Ohio.
The question for this game is which team can get its role players to step up the most. Both of these teams are incredibly well-coached and can find scoring from sources other than their stars. But that will be the top key to this game without so many big names on the floor.
Head‑to‑Head & Betting Trends
- Miami beat Cleveland 140-138 in overtime on Monday.
- This is the second of four regular-season games scheduled between the Cavs and Heat this season.
- The Heat have gone 8-3 against the spread so far this season.
- Cleveland is just 3-8 against the spread going into this game.
- The over has hit in 6 of Cleveland’s first 11 games.
- The over has hit 7 times in 11 games for the Heat.
Best Player Props to Watch
| Player | Prop |
|---|---|
| Norman Powell (Miami) | Over 23.5 Points |
| Jaime Jaquez Jr. (Miami) | Over 15.5 Points |
Cavaliers vs Heat Model Projection
Score Projection: Cleveland 106 – Miami 114
Win Probability: Cleveland 32% | Miami 68%
Final Thoughts
I don’t blame anyone for looking at the injury report for this game and staying far away from betting on it. I’m going ot take my chances with the Heat as a home favorite in this contest. Miami got a win over the Cavs just a couple of nights ago. They should build on that here with so many important players out for the Cavaliers.
