The Middle Tennessee Blue Raiders and Wisconsin Badgers will play in Week 2 of the college football season in Madison. Wisconsin got a shutout win over Miami (OH) to start their season while MIddle Tennessee lost to an FCS opponent in their opener. Wisconsin is a heavy favorite in light of those results. Here, I break down this non-conference game from Camp Randall Stadium and give you my Middle Tennessee vs Wisconsin prediction.
Our Middle Tennessee vs Wisconsin Pick
- Pick: Wisconsin −28.5
- Confidence: ★★★★★
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Game Snapshot
- Matchup: Middle Tennessee Blue Raiders vs Wisconsin Badgers
- Date & Time: Saturday, September 6, 2025, 4:00 p.m. ET
- Venue: Camp Randall Stadium, Madison, WI
- Broadcast: Fox Sports 1
Middle Tennessee vs Wisconsin Odds
| Spread | Total |
|---|---|
| Wisconsin −28.5 | 45.5 |
Key Storylines
- Wisconsin’s defensive dominance: Wisconsin pitched a shutout in their first game of the season against Miami (OH). That is an impressive performance against a good team from the MAC and Wisconsin is expected to shut down MTSU as well.
- Middle Tennessee’s offensive woes: Last week’s shock loss to FCS Austin Peay saw the Blue Raiders muster just 153 total yards and zero third-down conversions. They’ll need a major improvement to stay competitive.
- Backup QB in Madison: Wisconsin starting QB Billy Edwards Jr. exited early in Week 1. Danny O’Neil stepped in and managed the game but questions remain about the Badgers’ offensive upside in light of their quarterback situation.
- Motivation matters: Wisconsin is facing Alabama next week and will look to go into that marquee matchup with momentum. Middle Tennessee will simply look to reclaim its dignity after last week’s loss to an FCS opponent.
Quarterback Play
- Wisconsin (Danny O’Neil): Completed 12 of 19 passes for 120 yards with a touchdown and an interception in Week 1. It is unclear who will be under center in this game due to Edwards’ injury.
- Middle Tennessee (Nicholas Vattiato): Vattiato completed 16 of 37 passes for 104 yards and two touchdowns against FCS competition. That low completion rate is concerning going into a game against a team with a much better defense.
Betting Trends & H2H
- Both of these teams failed to cover the spread in their first games of the season.
- Both teams went under the total in their first game of the 2025 season.
- This is the first game between these two college football programs all-time.
Middle Tennessee vs Wisconsin Model Projection
Score Projection: Wisconsin 41 – Middle Tennessee 7
Win Probability: Wisconsin 99%, Middle Tennessee 1%
Final Thoughts
It would take nothing short of a miracle for Middle Tennessee to be competitive in this game, let alone winning the game. Wisconsin’s defense and running game should help them to control this contest from start to finish. I am going to lay the points with Wisconsin in this matchup with the expectation that they look much better offensively with some time to prepare for their quarterback situation ahead of this game.
