The Boston Celtics head to Philadelphia on Tuesday as underdogs to face the Philadelphia 76ers in an Atlantic Division clash. Each team has already split the first two games of the young season by a combined margin of two points. This third matchup carries early‑season significance for two teams trying to establish a consistent rhythm. Before tip-off from Philly, continue reading to get my Celtics vs 76ers prediction.
Our Celtics vs 76ers Pick
Pick: Philadelphia 76ers ‐1.5
Confidence: ★★★☆☆
Game Snapshot
- Matchup: Boston Celtics @ Philadelphia 76ers
- Date & Time: Tuesday, November 11, 2025, 8:00 p.m. ET
- Venue: Xfinity Mobile Arena, Philadelphia, Pennsylvania
- Broadcast: NBC / Peacock
Key Storylines
- Boston is missing Jayson Tatum (Achilles) for the season, which places more burden on Jaylen Brown, who is averaging 28 points per game. He could use help from the outside shooters of the Celtics as they look to win this game on the road.
- Philadelphia is getting stellar production from Tyrese Maxey. Maxey is averaging 33.2 points per game this season. He will have the help of Joel Embiid in this game, as Embiid is in the lineup despite being out sporadically due to injury management.
- Boston comes off a road win over the Orlando Magic, but their season has been marked by inconsistency. The Sixers have dropped three of their last four games and they will try to turn things around with a win in this matchup.
- Philadelphia has been better than the Celtics offensively this season, while the Celtics have been a better team on the defensive end of the floor. Whichever team does a better job of imposing their style on this game could come away with the win when all is said and done.
Head‑to‑Head & Betting Trends
- Boston is 4-7 against the spread going into this matchup.
- Philadelphia is 8-2 against the spread through 10 games.
- Philly is 7-3 to the over going into this game.
- The Celtics are 5-6 on over/unders entering this matchup from Philly.
Best Player Props to Watch
| Player | Prop |
|---|---|
| Tyrese Maxey (76ers) | Over 3.5 three‑pointers |
| Jaylen Brown (Celtics) | Over 27.5 points |
| Joel Embiid (76ers) | Over 21.5 points |
Celtics vs 76ers Model Projection
Score Projection: Boston Celtics 105 – Philadelphia 76ers 111
Win Probability: Celtics 35%, 76ers 65%
Final Thoughts
This should be another close game between the Celtics and Sixers, just like the ones we’ve seen between them earlier this season. I’m going to take the Sixers to get the win at home and to cover the spread. The Celtics are just a .500 team on the road this year and they should struggle in this road game with Embiid back on the floor for Philly.

