Washington Nationals vs Philadelphia Phillies Prediction – 8/22/2025

The Washington Nationals will head to Citizens Bank Park to face the Philadelphia Phillies on Friday evening. The Phillies come into this contest a four-game win streak and sit atop the National League East and the Nationals have won a couple games in a row themselves. Philadelphia comes in as a clear betting favorite as they search for their fifth straight victory. Continue reading to get my Nationals vs Phillies prediction for Friday night.

Our Nationals vs Phillies Pick

  • Pick: Over 9.5 runs
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Washington Nationals at Philadelphia Phillies
  • Date & Time: Friday, August 22, 2025, 6:45 PM ET
  • Starting Pitchers:
    • Nationals – Cade Cavalli (1–0, 2.20 ERA)
    • Phillies – Taijuan Walker (4–6, 3.34 ERA)
  • Stadium: Citizens Bank Park, Philadelphia, PA
  • Broadcast: NBCS-PH / MASN2

Key Storylines

Pitching matchup

Cade Cavalli has been impressive over a small sample size. He enters this start holding a 2.20 ERA over 16.1 innings and he delivered a dominant seven-inning performance in his last start. Taijuan Walker has been solid this season. He enters this game with a 3.34 ERA but is below .500 on the season and will look to get a win here.

Key Players

Kyle Schwarber and Bryce Harper are the power bats in this Phillies lineup. They will try to get Cavalli out of his rhythm in this contest. Washington’s bullpen will be their key in this game. The Nats have the highest bullpen ERA in baseball and will need to do better to shut down the Phillies.

Recent team streaks

  • The Phillies have won four straight games and swept the Seattle Mariners in their last series.
  • Washington has won two games in a row and beat the New York Mets in their last series.

Best Player Props

PlayerProp
Kyle SchwarberOver 0.5 Home Runs
Trea TurnerOver 1.5 Total Bases
James WoodOver 0.5 Home Runs
  • The Phillies lead the season series with the Nationals 6-4 this year.
  • These teams split a four-game series the last time they played each other.
  • Philly is 40-21 at home this season.
  • Washington is 26-36 in road games on the year.

Nationals vs Phillies Model Projection

Score Projection: Phillies 6 – Nationals 4

Win Probability: Phillies 60%, Nationals 40%

Final Thoughts

Both of these teams are performing well offensively of late. We just saw the Nationals put up some big numbers against a good Mets team and the Phillies are always capable of an offensive outburst. In this game, I think we see both teams continue to be in rhythm offensively. I’ll take the over in this contest and expect the Nats and Phillies to combine to score at least 10 total runs.


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Home MLB Picks Washington Nationals vs Philadelphia Phillies Prediction – 8/22/2025