San Diego Padres vs Seattle Mariners Prediction – 8/27/2025
The San Diego Padres and Seattle Mariners will close out their three-game series at T-Mobile Park on Wednesday afternoon. Both teams have taken a game from this series so far and will look to secure an important series win here. Before these teams battle it out in the Pacific Northwest, you can find my Padres vs Mariners prediction below.
Our Padres vs Mariners Pick
- Pick: Seattle Mariners Moneyline
- Confidence: ★★★★☆
- Claim Your Bonus Bets: Click the Claim Bonus button below to claim our DraftKings Sportsbook bonus. You can bet $5 and get $300 in bonus bets INSTANTLY and over $200 off NFL Sunday Ticket!
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Matchup: San Diego Padres at Seattle Mariners
- Date & Time: Wednesday, August 27, 2025, 4:10 p.m. ET
- Starting Pitchers:
- Padres – Yu Darvish (3-3, 5.36 ERA)
- Mariners – Bryan Woo (11-7, 2.94 ERA)
- Stadium: T-Mobile Park, Seattle, WA
- Broadcast: MLB Network
Key Storylines
Pitching matchup
Seattle’s Bryan Woo has delivered a remarkably consistent season for the Mariners. The AL All-Star enters this game with an ERA under 3.00 across a heavy workload. He has had multiple quality starts in August and will look to lead his team to a win in his final start of August today. Yu Darvish’s campaign has been patchy. His 5.36 ERA is better than it was just a couple of weeks ago. But there are still concerns about Darvish’s dependability right now.
Key Players
- Ramon Laureano hit a grand slam for the Padres last night and helped them get a much-needed victory on the road.
- Cal Raleigh has hit 50 home runs for the Mariners and has become a player in the AL MVP race for the season. He will be key to his team’s success again in this matchup.
Recent team streaks
- The Padres snapped a two-game skid with a 7-6 win on Tuesday.
- The Mariners had won two straight games and three of their last four prior to Tuesday’s defeat.
Best Player Props
| Player | Prop |
|---|---|
| Cal Raleigh | Over 0.5 Home Runs |
| Fernando Tatis Jr. | Under 1.5 Total Bases |
Betting Trends & H2H
- The Mariners hold a 4-1 lead in their season series against the Padres.
- Seattle had won four straight games over San Diego before Tuesday’s win for the visitors.
- San Diego is 29-17 in day games on the season.
- Seattle is 28-20 in day games in 2025.
Padres vs Mariners Model Projection
Score Projection: Mariners 5 – Padres 4
Win Probability: Mariners 53%, Padres 47%
Final Thoughts
Seattle holds the edge in this series finale. Bryan Woo’s reliable pitching and the ability to change any game with a swing by Cal Raleigh should work in their favor in this contest. I will take the Mariners to win this contest between two teams that are desperate to close the distance on the leaders of their respective divisions today.
