San Diego Padres vs Philadelphia Phillies Game 2 Prediction – 7/2/2025

The San Diego Padres and Philadelphia Phillies will battle in Game 2 of Wednesday’s doubleheader at Citizens Bank Park. Philadelphia rolls into this game favored at home, but with such a good pitching matchup, this game could go either way. Here, I break it all down and give you my Padres vs Phillies Game 2 prediction.

Our Padres vs Phillies Game 2 Pick

• Pick: Padres moneyline (+128)
• Confidence: ★★★☆☆
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Game Snapshot

• Matchup: San Diego Padres at Philadelphia Phillies
• Date & Time: Wednesday, July 2, 2025, 6:15 PM EDT
• Starting Pitchers: Cristopher Sánchez (PHI) vs Dylan Cease (SD)
• Stadium: Citizens Bank Park, Philadelphia, PA
• Broadcast: NBC Sports Philadelphia

Key Storylines

Pitching Form

• Cristopher Sánchez has logged a 2.79 ERA over 16 starts, including 103 strikeouts. His last outing featured 11 punchouts over six innings, although he took a loss to the Houston Astros in that matchup.
• Dylan Cease will get the ball for the Padres in Game 2 of their doubleheader today. Cease is 3-7 with a 4.53 ERA and gave up two home runs in a loss to the Cincinnati Reds in his last start, which he will look to bounce back from.

Bullpen Usage

Both teams appear primed for a challenge going into this contest. Their bullpens will likely get some work in the opening game of this doubleheader. That will require their managers to work with fewer arms than they are used to, which could yield some interesting situational managing late in the game.

Recent Team Streaks

• The Phillies enter this game on a two-game winning streak, including a 4-0 win over the Padres in the first game of this series.
• The Padres have lost two straight games and three of their last four, dropping a series to the Cincinnati Reds before losing in Philly on Monday.

Padres vs Phillies Game 2 Model Projection

Score Projection: Padres 4 – Phillies 3

Win Probability: Padres 48%, Phillies 52%

Final Thoughts

This game looks like a potential pitcher’s duel with two reliable arms and strong bullpens on both sides. Philadelphia enters as the favorite, but Cease has a high ceiling, even if he has had his share of struggles throughout this season. I’ll take the Padres on the moneyline as an underdog here, as it is hard for any team to sweep a doubleheader in this league, but you may want to see how Game 1 plays out before making any wagering decisions.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.