San Diego Padres vs Miami Marlins Pick – 7/22/2025
The San Diego Padres and Miami Marlins will renew their hostilities at loanDepot Park in Game 2 of a three‑game set on Tuesday night. The first game ended in a tight 2‑1 win for San Diego. Miami will look to bounce back in what is virtually a pick ’em game. Here, we take a closer look at this National League contest and bring you our Padres vs Marlins prediction for this matchup. Kolek has had mixed results for the Padres this year. He is 3‑4 with a 4.24 ERA and 1.29 WHIP. He’s typically pitched between 4–7 innings per outing. This marks his first appearance against Miami of 2025. Cabrera is also 3-4 this season but has a slightly better ERA than Kolek does. His control and solid strikeout numbers make him the stronger of the two starters in this contest. Both bullpens in this matchup should be set up nicely for success in this game. They weren’t pushed too hard in Monday’s series opener and both teams had success shutting the opposition down for the most part. San Diego has the better bullpen ERA for the season but both teams proved yesterday they can get the job done with their relievers. Score Projection: Padres 4 – Marlins 5 Win Probability: Padres 46%, Marlins 54% This should be another low‑scoring affair between the Padres and Marlins. Both bullpens should perform well again in this game. But I give a slight edge to the Marlins thanks to Cabrera’s superiority in the starting pitching department compared to Kolek. This game will be close throughout, but I recommend taking the Marlins to win it and to even this series at a game apiece.Our Padres vs Marlins Pick
Game Snapshot
Key Storylines
Pitching Form
Bullpen Usage
Recent Team Streaks
Best Player Props
Player Prop Pick Kyle Stowers (MIA) Home runs Over 0.5 Edward Cabrera (MIA) Strikeouts Over 5.5 Luis Arraez (SD) Total bases Over 1.5 Betting Trends & H2H
Padres vs Marlins Model Projection
Final Thoughts
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