Philadelphia Phillies vs Cincinnati Reds Pick – 8/13/2025

Cincinnati will be the site of the final game of the three-game series between the Philadelphia Phillies and Cincinnati Reds on Wednesday. Each team has taken a game in this series so far and Wednesday’s winner will secure an important series win. I have taken a deep dive into the numbers surrounding this game and below you can find my Phillies vs Reds prediction.

Our Phillies vs Reds Pick

  • Pick: Reds moneyline
  • Confidence: 2/5
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Game Snapshot

  • Matchup: Philadelphia Phillies vs Cincinnati Reds
  • Date & Time: Wednesday, August 13, 2025, 5:10 p.m. ET
  • Starting Pitchers: Cristopher Sanchez (11–3, 2.36 ERA) vs Hunter Greene (4–3, 2.72 ERA)
  • Stadium: Great American Ball Park, Cincinnati, OH
  • Broadcast: FanDuel Sports Network Ohio and NBCS-PH

Key Storylines

Pitching Matchup

Cristopher Sanchez is having a dominant 2025 season for Philadelphia. He has an 11–3 record with a 2.36 ERA and 151 strikeouts over 144.2 innings. Opposing him is Hunter Greene. Greene is also having a good season. He is 4-3 with a 2.72 ERA over 59.2 innings and he certainly has the potential to go toe-to-toe with Sanchez.

Key Players

  • Phillies: Bryce Harper hit a home run to produce the only run for the Phillies on Tuesday. He will be a vital part of the Phillies’ lineup again on Wednesday night.
  • Reds: Spencer Steer will aim to build on a big Tuesday night. Steer knocked in three runs in Cincinnati’s 6-1 win over the Phillies.

Recent Team Streaks

  • The Phillies have won four of their last five games with their winning streak coming to an end on Tuesday.
  • Cincinnati has won three of its last four games going into this matchup.

Best Player Props

PlayerHome Runs
Kyle SchwarberOver 0.5 Home Runs
Hunter GreeneOver 5.5 Strikeouts
  • The Phillies hold a 3-2 lead in the season series against the Marlins.
  • Miami’s win over Philadelphia on Tuesday snapped a three-game winning streak for the Phillies over the Marlins.
  • Cincinnati is just 40-42 against National League teams.
  • Philadelphia is 45-35 in games against NL opponents.

Phillies vs Reds Model Projection

Score Projection: Reds 5 – Phillies 4

Win Probability: Reds 51%, Phillies 49%

Final Thoughts

Both teams have elite starting pitching on their side in this matchup. I think this game will come down to the bullpens and that bodes well for the Reds. Home-field advantage also bodes well for Cincinnati. The Reds improved to 34-27 at home with their win over Philly on Tuesday. I think that number will be improved to 35-27 with a Cincinnati victory in this contest.


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Home MLB Picks Philadelphia Phillies vs Cincinnati Reds Pick – 8/13/2025