Philadelphia Phillies vs Chicago White Sox Prediction – 7/29/2025
The Philadelphia Phillies will face the Chicago White Sox at Rate Field on Tuesday night. The White Sox shocked the Phillies in the opening game of this series from Chicago. They will look to sow more seeds of doubt in the minds of the Phillies tonight. Continue reading to get my Phillies vs White Sox prediction for this interleague game.
Our Phillies vs White Sox Pick
- Pick: White Sox Moneyline
- Confidence: ★★★★☆
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Game Snapshot
| Matchup | Philadelphia Phillies vs. Chicago White Sox |
| Date & Time | July 29, 2025, 7:40 PM ET |
| Starting Pitchers | Jesus Luzardo vs. Jonathan Cannon |
| Stadium | Rate Field, Chicago, IL |
| Broadcast | MLB.tv |
Key Storylines to Watch
Pitching Duel: Jesus Luzardo gets the start for the Phillies tonight. Luzardo is 8-5 for the season but his 4.58 ERA indicates he is more vulnerable than his record would suggest. Jonathan Cannon will take the mound for the White Sox in this game. Cannon is 4-7 with a 4.48 ERA. He has been better than Luzardo individually but has been a victim of his team’s lower quality.
Bullpen Status: Philadelphia’s bullpen has been better over the long run this season. But the White Sox won the bullpen battle on Monday and will look to do so again in this contest.
Team Momentum: The White Sox have won three of their last five games. They snapped a two-game losing streak with their win over Philly on Monday. The Phillies have dropped three of their last five games.
Best Player Props
| Kyle Schwarber | Home Runs | Over 0.5 |
| Jonathan Cannon | Strikeouts | Over 5.5 |
| Luis Robert Jr. | Total Bases | Over 1.5 |
Betting Trends & Head-to-Head
The Phillies won the lone game of the season series between these teams this year.
The first game of this series went under the total of 8.5 runs.
The Phillies are just 27-27 on the road for the season after their loss on Monday in Chicago.
Phillies vs White Sox Model Projection
Projected Score: White Sox 4 – Phillies 2
Win Probability: White Sox 50% | Phillies 50%
Final Thoughts
The Philadelphia Phillies are a much better team than the Chicago White Sox on paper. But baseball is not played on paper, as we all saw when these teams met on Monday. I think the White Sox are a sneaky good value play with Cannon on the mound on Tuesday and I will take Chicago at a plus price to pull the upset.
