Minnesota Twins vs Los Angeles Dodgers Pick – 7/22/2025
The Los Angeles Dodgers snapped a three-game losing streak with a win over the Minnesota Twins on Monday night. They will look for a repeat performance on Tuesday with the Dodgers having a chance to reach the 60-win mark with a victory at home. Los Angeles is favored with Yoshinobu Yamamoto on the mound in this contest. Continue reading to get my Twins vs Dodgers prediction for the second game of this interleague series.
Our Twins vs Dodgers Pick
Pick: Dodgers -1.5
Confidence: 4 stars
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Starting Pitchers: Simeon Woods Richardson (MIN) vs Yoshinobu Yamamoto (LAD)
Stadium: Dodger Stadium, Los Angeles, CA
Broadcast: MLB Network, SportsNet LA, and MNNT
Key Storylines
Pitching Form: Yoshinobu Yamamoto enters the game with an 8-7 record and an impressive 2.59 ERA. He has allowed just 73 hits in 104.1 innings and has been great at missing bats all season long. Simeon Woods Richardson of the Twins is making his first career start against the Dodgers. He is 5-4 on the year and has a solid 3.95 ERA.
Bullpen Usage: The Dodgers’ bullpen helped them shut the door on Monday’s win over the Twins. Both pens gave up just one run in that contest and both groups of relievers should be largely fresh for this game.
Recent Team Streaks: Minnesota’s loss on Monday was their fourth loss in five games. The Dodgers are 2-3 in their last five contests. Their win over the Twins in the opening game of this series snapped a three-game losing streak.
Best Player Props
Player
Prop
Byron Buxton
Over 0.5 Home Runs
Yoshinobu Yamamoto
Over 7.5 Strikeouts
Shohei Ohtani
Over 0.5 Home Runs
Betting Trends & H2H
These teams have played just once so far this season. The Dodgers won that game on Monday night at home.
The Dodgers are 34-20 at home after Monday’s win. The Twins dropped to 20-32 on the road with the loss.
The first game of this series went under the total, with seven total runs being scored.
Twins vs Dodgers Model Projection
Score Projection: Twins 3 – Dodgers 6
Win Probability: Twins 18%, Dodgers 82%
Final Thoughts
I expect the Dodgers to win and cover the runline for the second straight game over the Minnesota Twins. Yamamoto should give the Dodgers at least five solid innings in this game. And with Ohtani and the Dodgers offense starting to break out of its mini-slump last night, I think we see a big offensive performance from the home team here.
Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.
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Home›MLB Picks›Minnesota Twins vs Los Angeles Dodgers Pick – 7/22/2025
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