Houston Astros vs Boston Red Sox Pick – 8/1/2025

The Houston Astros and Boston Red Sox will do battle on Friday night at Fenway Park. Both of these teams are in playoff positions going into their series this weekend and will look to improve on those positions with a win in this contest. For a full breakdown of this American League matchup, including my Astros vs Red Sox prediction, continue reading right here.


Our Astros vs Red Sox Pick

  • Pick: Astros Moneyline
  • Confidence: ★★★★☆
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Game Snapshot

MatchupHouston Astros vs. Boston Red Sox
Date & TimeAugust 1, 2025, 7:10 PM ET
Starting PitchersHunter Brown (HOU) vs. Undecided (BOS)
StadiumFenway Park, Boston, MA
BroadcastApple TV+

Key Storylines to Watch

  • Pitching Matchup: Hunter Brown has been stellar this season for the Astros. He is 9-5 for the season with a 2.54 ERA. Brown has pitched very well on the road this season. He is 5-2 with a 2.70 ERA in 11 road starts this year. The Red Sox have yet to decide on a starting pitcher for this game and that will be an interesting situation to monitor.

  • Bullpen Usage: Both bullpens are well rested after getting Thursday off before the start of this series. Both of these bullpens rank in the top five in the league in bullpen ERA and both teams could struggle to score late in this game.

  • Team Momentum: Both teams have won two straight games going into this contest. The Astros won two out of three games against the Washington Nationals in their last series. The Red Sox took two out of three from a Minnesota Twins team that was too busy selling at the trade deadline to compete.


Best Player Props

PlayerPropPick
Jose AltuveTotal BasesOver 1.5
Alex BregmanHome RunsOver 0.5
Hunter BrownStrikeoutsOver 6.5

  • This is the first meeting between these teams in 2025.
  • The Astros and Red Sox will play a total of six times over the next two weeks.
  • Houston is 27-23 on the road for the season.
  • Boston is an impressive 34-21 at Fenway Park this year.

Astros vs Red Sox Model Projection

Projected Score: Astros 5 – Red Sox 3
Win Probability: Astros 60% | Red Sox 40%


Final Thoughts

The starting pitching situation for this game should work in the favor of the Houston Astros. Houston has a very good starting pitcher on the hill in Hunter Brown. Even when Boston does decide which route they are going to take on the mound, it is unlikely that pitcher will be as good as Brown is. I will take the Astros to win this game on the road as they look to maintain their cushion over the Seattle Mariners in the AL West standings.


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Home MLB Picks Houston Astros vs Boston Red Sox Pick – 8/1/2025