Chicago Cubs vs San Francisco Giants Prediction – 8/26/2025
The Chicago Cubs will open a three-game series against the San Francisco Giants on Tuesday night at Oracle Park. The Cubs are at the top of the NL Wild Card standings while the Giants are looking to get themselves back into Wild Card contention. Before this game begins from the Bay Area, continue reading to get my Cubs vs Giants prediction for tonight.
Our Cubs vs Giants Pick
- Pick: Chicago Cubs -1.5
- Confidence: 4/5
- Claim Your Bonus Bets: Click the Claim Bonus button below to claim our DraftKings Sportsbook promo. You can bet $5 and get $300 in bonus bets INSTANTLY and over $200 off NFL Sunday Ticket!
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Matchup: Chicago Cubs vs San Francisco Giants
- Date & Time: Tuesday, August 26, 2025, 9:45 PM EDT
- Starting Pitchers: Matthew Boyd (Cubs) vs Justin Verlander (Giants)
- Stadium: Oracle Park, San Francisco, CA
- Broadcast: NBC Bay Area, Marquee Sports Network
Key Storylines
Pitching Matchup
Matthew Boyd (12-6, 2.61 ERA) takes the mound for the Cubs. The left-hander has been a consistent force this season. He has a 12-6 record, 2.61 ERA, and 129 strikeouts over 148 innings. Boyd’s recent performance includes a win against the Brewers. He allowed four earned runs over 5.1 innings but still managed to get the win thanks to some run support.
Opposing Boyd is the struggling Justin Verlander. Verlander is 1-10 with a 4.64 ERA on the year for the Giants. The veteran right-hander has struggled this season in disappointing fashion. Verlander’s most recent start was a loss to the Padres. He allowed eight earned runs over seven innings and will look to tighten things up in this contest.
Key Players
- Pete Crow-Armstrong (Cubs): Crow-Armstrong is leading the Cubs with 28 home runs. PCA has been a consistent threat in the Cubs’ lineup.
- Seiya Suzuki (Cubs): Suzuki has a team-best 87 RBIs and has helped generate runs in high-leverage spots for Chicago.
- Willy Adames (Giants): The Giants’ shortstop has 22 home runs and 65 RBI and will be key to elevate the pitch count of Boyd tonight.
Recent Team Streaks
- The Cubs have won three games in a row and they have four wins in their last five matchups.
- The Giants have won two games in a row and they are 2-3 in their last five outings.
Best Player Props
| Player | Prop |
|---|---|
| Nico Hoerner | Over 1.5 Total Bases |
| Seiya Suzuki | Over 0.5 Home Runs |
| Matthew Boyd | Over 17.5 Outs Recorded |
Betting Trends & H2H
- The Giants have a 2-1 lead in their season series against the Cubs this year.
- Chicago is 35-30 in road games this season.
- San Francisco is 30-33 in their home games during the 2025 campaign.
Cubs vs Giants Model Projection
- Score Projection: Cubs 6 – Giants 4
- Win Probability: Cubs 58%, Giants 42%
Final Thoughts
The Cubs have a clear advantage on the mound for this game. Verlander’s struggles should give Chicago the upper hand in the early innings and that should help Chicago to win this game with some margin. I will lay the runline with the Cubs at plus money tonight.
