Arizona Diamondbacks vs Milwaukee Brewers Prediction – 8/28/2025

The Arizona Diamondbacks and Milwaukee Brewers will close out their four-game series in Milwaukee on Thursday afternoon. Both teams are looking for wins for different reasons here. Arizona is trying to help its slim Wild Card chances and Milwaukee is trying to move closer to home-field advantage in the postseason. Before the action begins from Wisconsin, continue reading below to get my Diamondbacks vs Brewers prediction for Thursday.

Our Diamondbacks vs Brewers Pick

  • Pick: Milwaukee Brewers -1.5
  • Confidence: 3/5
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Game Snapshot

  • Matchup: Arizona Diamondbacks vs Milwaukee Brewers
  • Date & Time: Thursday, August 28, 2025, 2:10 p.m. ET
  • Starting Pitchers:
    • Brewers: José Quintana (10-4, 3.32 ERA)
    • Diamondbacks: Nabil Crismatt (1-0, 1.00 ERA)
  • Stadium: American Family Field, Milwaukee, WI
  • Broadcast: MLB Network

Key Storylines

Pitching matchup

José Quintana takes the mound for Milwaukee in his 21st start of the season. He’s posted a solid 3.32 ERA over 111.2 innings and has reached double-digits in wins. Quintana’s FIP is higher than his ERA but he isn’t expected to regress dramatically. Nabil Crismatt makes just his third appearance of the season after allowing one run over nine innings in his first two. We haven’t seen enough of Crismatt to make any sweeping determinations about his future but he’s off to a promising start.

Key Players

  • William Contreras is in fine form and hit a home run in yesterday’s loss for the Brewers.
  • Geraldo Perdomo has been hot for Arizona. His home run in the eighth inning last night gave the Diamondbacks an insurance run that ended up keeping them ahead for good.

Recent team streaks

  • The Diamondbacks ended a three-game losing streak with their victory at home over the Brewers on Wednesday night.
  • Milwaukee has won two of the first three games of this series and had a two-game winning streak broken in their last game.

Best Player Props

PlayerProp
Christian YelichOver 1.5 Total Bases
William ContrerasOver 0.5 Home Runs
Geraldo PerdomoUnder 1.5 Total Bases
  • The season series between these teams is tied 3-3.
  • This is the final game of the regular-season series between these two clubs. The winner of this game will win the season series.
  • Arizona is 31-37 on the road so far this year.
  • The Brewers hold an impressive 45-23 home record despite Wednesday’s loss at home.

Diamondbacks vs Brewers Model Projection

Score Projection: Brewers 5 – Diamondbacks 3

Win Probability: Brewers 58%, Diamondbacks 42%

Final Thoughts

The Milwaukee Brewers are at home and have a significant starting pitching advantage in this contest. I am expecting some regression from Nabil Crismatt on the hill for Arizona here and for the Brewers to claim the season series with a win over the snakes. My best bet for this game is for the Brewers to cover the runline, as they should win by two runs or more with Quintana pitching.


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Home MLB Picks Arizona Diamondbacks vs Milwaukee Brewers Prediction – 8/28/2025