Washington Nationals vs Miami Marlins Pick – 9/10/2025

The Washington Nationals and Miami Marlins have played two high-scoring games during their current four-game series. They will meet again on Wednesday night in the third game of that four-game set. Washington has won the first two games of the series and will look for a third in a row on the road against a Marlins team that has struggled mightily on the mound of late. Here, I break down this NL East matchup and bring you my Nationals vs Marlins prediction.

Our Nationals vs Marlins Pick

  • Pick: Marlins -1.5
  • Confidence: 3/5
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Game Snapshot

  • Matchup: Washington Nationals vs Miami Marlins
  • Date & Time: Wednesday, September 10, 2025, 6:40 p.m. ET
  • Starting Pitchers: Jake Irvin vs Eury Pérez
  • Stadium: loanDepot park, Miami, FL
  • Broadcast: FD Sports Florida, MASN 2

Key Storylines

  • The Nationals have won the first two games of this series and they are playing some of their best baseball late in the regular season. It is too late for the Nats to mount a playoff push but they will be encouraged by their recent level of play.
  • Pitchers have struggled across the board in this series so far. There have been a combined 34 runs through the first two games of this series and someone will have to step up on the mound in this game for the scoring to cease.

Pitching matchup

  • Jake Irvin of the Nationals is 8-11 with a 5.71 ERA and a 1.44 WHIP. He is a flyball pitcher and that has resulted in him allowing 33 home runs this season. The Nats will need him to keep the ball in the park here if they are going to continue their winning ways.
  • Eury Pérez is 6-5 with a 4.66 ERA for the Marlins this season. Perez has struggled since returning from injury and will try to bounce back from his recent woes here.

Recent team streaks

  • The Nationals have won the first two games of this series and four games in a row overall.
  • Miami has dropped two straight games and four of their last five.

Best Player Props

PlayerProp
James WoodUnder 1.5 Total Bases
CJ AbramsUnder 1.5 Total Bases
Eury PérezOver 5.5 Strikeouts
Jake IrvinUnder 5.5 Strikeouts
  • Washington took a 6-5 lead in their season series against the Nationals with their win on Tuesday.
  • Washington has won five straight games over the Marlins over the course of this season.

Nationals vs Marlins Model Projection

Score Projection: Nationals 3 – Marlins 5

Win Probability: Nationals 42%, Marlins 58%

Final Thoughts

This seems like a great opportunity for the Marlins to get back on track after some recent struggles. Perez gives the Marlins the advantage on the mound in this game and that should help them to get a win at home. I recommend laying the runline with the Marlins as they should end the Nats’ winning streak on Wednesday night.


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Home MLB Picks Washington Nationals vs Miami Marlins Pick – 9/10/2025