Washington Nationals vs Houston Astros Prediction – 7/29/2025

The Houston Astros will host the Washington Nationals at Daikin Park on Tuesday night. The Astros aim to snap a five-game losing streak. The Nationals come in seeking their fourth consecutive win. Before the Nationals and Astros do battle on the diamond, continue reading to get my Nationals vs Astros prediction for Tuesday night.


Our Nationals vs Astros Pick

  • Pick: Nationals Moneyline
  • Confidence: ★★★★☆
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Game Snapshot

MatchupWashington Nationals vs. Houston Astros
Date & TimeJuly 29, 2025, 8:10 p.m. ET
Starting PitchersMichael Soroka (WSH) vs. Jason Alexander (HOU)
StadiumDaikin Park, Houston, TX
BroadcastMASN2, SCHN

Key Storylines to Watch

  • Pitching Form: Jason Alexander will take on Michael Soroka in the starting pitching matchup for this game. Alexander is 1-1 with an 8.14 ERA for Houston this season. Soroka is 3-8 with a 4.85 ERA. The pitcher who can find a more consistent start to this game will give their team a big advantage in this interleague game.

  • Bullpen Usage: Both bullpens pitched well in last night’s 2-1 win for the Nationals. The Astros have the fifth-best bullpen ERA in baseball and will look to use their pen to bounce back from last night’s loss.

  • Team Momentum: The Nationals have won three straight games going into this contest and will look to continue that streak. The Astros are looking to snap a dismal run in which they have lost five straight games.


Best Player Props

PlayerPropPick
James WoodHome RunsOver 0.5
Jeremy PeñaTotal BasesOver 1.5

  • The Nationals lead the season series between these teams 1-0.

  • The first game of the year between these teams on Monday went under the total comfortably.

  • The Nationals have allowed three runs or fewer in four straight games.

Nationals vs Astros Model Projection

Projected Score: Nationals 5 – Astros 3
Win Probability: Astros 50% | Nationals 50%


Final Thoughts

The Astros had a huge pitching advantage on Monday night and still could not beat the Nationals. They do not have the pitching edge tonight with the inexperienced Alexander on the bump. I will take the Nats to win in an upset in this game, as neither starting pitcher is reliable enough to lay significant juice with a favorite.


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Home MLB Picks Washington Nationals vs Houston Astros Prediction – 7/29/2025