Washington Nationals vs Chicago Cubs Pick – 9/7/2025

The Chicago Cubs and Washington Nationals will meet on Sunday afternoon at Wrigley Field. These are two teams with very different agendas late in the regular season. Chicago is trying to finish with the best playoff position possible, while the Nats are simply playing for pride late in the year. Before these National League opponents do battle on the diamond, continue reading to get my Nationals vs Cubs prediction.

Our Nationals vs Cubs Pick

  • Pick: Over 8.5
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Washington Nationals vs Chicago Cubs
  • Date and Time: Sunday, September 7, 2025, 2:20 p.m. ET
  • Starting Pitchers: Andrew Alvarez vs Drew Pomeranz
  • Stadium: Wrigley Field, Chicago, IL
  • Broadcast: Marquee Sports Network and MASN2

Key Storylines

  • Andrew Alvarez impressed in his MLB debut with five scoreless innings and one hit allowed on 81 pitches. He will try to prove himself as more than a one-hit wonder in this contest.
  • Drew Pomeranz is set to get the start in this game out of the bullpen. This being a bullpen day for the Cubs will make things interesting for them as they are going to have to navigate a ton of innings without a true starting pitcher to eat up the majority of them.

Pitching matchup

Andrew Alvarez has a sharp curve and a slider he trusts to both edges of the plate. His debut was efficient and composed. But he will be tasked with pitching that well against a very good Cubs team here. Pomeranz has not pitched more than 1.1 innings in a game this season. That means we are going to see a lot of the Chicago bullpen here, for better or worse.

Recent team streaks

  • The Nationals have won four of their last five games and have clearly not given up despite being out of playoff contention.
  • Chicago has dropped two of its last three games.

Best Player Props

PlayerProp
Seiya SuzukiTo hit a HR
James WoodTo hit a HR
Andrew AlvarezUnder 4.5 Ks
Pete Crow-ArmstrongOver 1.5 TB
Ian HappOver 1.5 TB
  • The Cubs hold a 3-2 lead in their season series against the Nationals.
  • This is the final game of the season series between these teams.
  • The road teams are 3-2 in matchups between the Cubs and Nats this year.

Nationals vs Cubs Model Projection

Score Projection: Washington 3 – Chicago 6

Win Probability: Washington 36%, Chicago 64%

Final Thoughts

The pitching situation on both sides is concerning going into this game. You have an inexperienced starter on the bump for the Nationals and the Cubs are taking on a bullpen day. As a result, I think that the over is the best bet in this game instead of trusting either team’s pitching staff to deliver a win. I’ll take the over at 8.5 runs and bank on a high-scoring game in Chicago.


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Home MLB Picks Washington Nationals vs Chicago Cubs Pick – 9/7/2025