Toronto Blue Jays vs Tampa Bay Rays Prediction – 9/15/2025

The Toronto Blue Jays will open a huge four-game set against the Tampa Bay Rays on Monday night. The Blue Jays are at the top of the AL East standings and looking to move one step closer to the division title. Tampa’s playoff hopes are on life support coming down the stretch of the regular season. Here, I break down this AL East matchup and give you my Blue Jays vs Rays prediction for Monday’s series opener.

Our Blue Jays vs Rays Pick

• Pick: Rays moneyline
• Confidence: ★★★☆☆
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Game Snapshot

• Matchup: Toronto Blue Jays vs Tampa Bay Rays
• Date & Time: September 15, 2025, 7:35 PM ET
• Starting Pitchers: Trey Yesavage (TOR) vs Undecided (TB)
• Stadium: George M. Steinbrenner Field, Tampa, FL
• Broadcast: MLB.TV

Key Storylines

• The pitching matchup is interesting in this game. The Jays are starting Trey Yesavage in this contest. He is making his MLB debut at the age of 22 and will look to make a positive first impression in this contest. Tampa has yet to decide on who their starting pitcher is going to be in this game and that decision will have a huge impact on the outcome of this matchup.
• Bichette’s status: Toronto’s shortstop is on the 10-day injured list with a knee sprain. He owns a .311 average with 18 homers and 93 RBI. His absence shifts more offensive responsibilities to George Springer, Vladimir Guerrero Jr., and Andrés Giménez.
• The Blue Jays are four games up on the New York Yankees in the AL East title race. They are in the driver’s seat in that race but need to finish strong to close things out.
• Tampa is 7.5 games back of the final AL Wild Card spot and they need to win almost all of their remaining games to have a chance at the postseason.

Key Players

• Blue Jays: George Springer’s power is spiking again after the calendar turned to September. Vladimir Guerrero Jr. provides power as well. Both hitters will be of vital importance with Bichette out.
• Rays: Junior Caminero has plus bat speed and lift to left center. That makes him a constant extra-base threat. Yandy Díaz grinds at-bats and lengthens innings for opposing pitchers.

Recent team streaks

• The Jays have won four games in a row going into Monday’s series opener.
• Tampa is 1-4 over their last five games going into tonight.

Best Player Props

Betting Trends & H2H

• The Rays lead the season series 5-1 over the Blue Jays in 2025.
• These teams are set to play seven games against each other over the final two weeks o fthe regular season.

Blue Jays vs Rays Model Projection

Score Projection: Blue Jays 3 – Rays 4

Win Probability: Blue Jays 45%, Rays 55%

Final Thoughts

The starting pitching situation makes this game a nightmare to handicap. But I think that we are going to see the Rays compete in this contest at home despite not knowing tho they are going to start on the mound. I’ll take Tampa at a plus price to win this contest and make the AL East race closer.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.