Toronto Blue Jays vs Cincinnati Reds Prediction – 9/2/2025

The Toronto Blue Jays and Cincinnati Reds will continue their interleague series on Tuesday night. Toronto is fighting to maintain control of the AL East and the Reds are hanging onto their postseason hopes by a thread. Cincinnati won the first game of this series and will try to make it two in a row against the Jays in this contest. Before the second game of this interleague series, continue reading to get my Blue Jays vs Reds prediction.

Our Blue Jays vs Reds Pick

  • Pick: Reds moneyline
  • Confidence: 4/5 stars
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Game Snapshot

  • Matchup: Toronto Blue Jays vs Cincinnati Reds
  • Date & Time: Tuesday, September 2, 2025, 6:40 PM
  • Starting Pitchers: Jose Berrios (TOR) vs Nick Lodolo (CIN)
  • Stadium: Great American Ball Park, Cincinnati, OH
  • Broadcast: Bally Sports Ohio / Sportsnet

Key Storylines

  • Toronto holds a 79-59 record, leading the Yankees by 2.5 games in the AL East.
  • Cincinnati has dropped seven of its last 10 games and have slipped in the NL Wild Card race.
  • Cincinnati won the first game of this series on Monday.

Pitching Matchup

Jose Berrios will get the start for the Blue Jays on Tuesday. He is 9-5 and has a 3.95 ERA on the year. Berrios will be opposed by Nick Lodolo of the Reds on the bump. Lodolo is 8-7 and has a 3.22 ERA. Lodolo’s individual talent is not being done justice by his win-loss record but the overall body of work from Lodolo this year has been impressive.

Key Players

  • Toronto: Bo Bichette and Dalton Varsho both hit a home run and scored two runs in the Jays’ loss on Monday.
  • Cincinnati: Noelvi Marte had a walk-off hit for the Reds yesterday and he continues to make timely plays for his team.

Recent Team Streaks

  • The Blue Jays have lost three of their last four games entering tonight’s action.
  • Cincinnati has won two games in a row and will look to continue that streak here.

Best Player Props

PlayerProp
Vladimir Guerrero Jr.Under 1.5 Total Bases
Nick LodoloOver 5.5 Strikeouts
Bo BichetteOver 1.5 Total Bases
  • The Reds lead the Blue Jays 1-0 in their season series this year.
  • The first game between these teams finished 5-4 and went just over the total.
  • Toronto dropped to 34-35 on the road with Monday’s loss.
  • Cincinnati is 38-31 at home for the season.

Blue Jays vs Reds Model Projection

Score Projection: Reds 5 – Blue Jays 3

Win Probability: Reds 59%, Blue Jays 41%

Final Thoughts

The Cincinnati Reds are at home against a team with a sub-.500 road record. Cincinnati also has a starting pitching edge in this contest with Lodolo on the bump. All of that should lead up to the Reds getting a win at home on Tuesday night. I’ll take the Reds as the slightest of moneyline favorites in this National League showdown.


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Home MLB Picks Toronto Blue Jays vs Cincinnati Reds Prediction – 9/2/2025