Toronto Blue Jays vs Cincinnati Reds Pick – 9/3/2025

The Toronto Blue Jays and Cincinnati Reds have split their two games against each other this week. They will play for the third and final time on Wednesday night at Great American Ball Park. Both teams are sending solid starting pitchers to the mound and we could be in for a game where just a couple of runs could make the difference. Before the first pitch from Cincinnati, continue reading for my Blue Jays vs Reds prediction.

Our Blue Jays vs Reds Pick

  • Pick: Cincinnati Reds to win
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Toronto Blue Jays vs Cincinnati Reds
  • Date & Time: Wednesday, September 3, 2025, 6:40 p.m. ET
  • Starting Pitchers: Shane Bieber (1–1, 2.38 ERA) vs Zack Littell (9–8, 3.63 ERA)
  • Stadium: Great American Ball Park, Cincinnati, OH
  • Broadcast: FDSOH and SNET

Key Storylines

Pitching matchup

Toronto will send Shane Bieber to the mound. He’s posted a stellar 2.38 ERA across two starts with an impressive 11.9 strikeouts per nine innings. Opponents are batting just .175 against him so far. He’ll be looking to push his team to victory after allowing two earned runs over 5.1 innings in his last outing.

Cincinnati will give the ball to Zack Littell. Littell has a solid 3.63 ERA and has delivered 16 quality starts in 27 appearances. Littell logged seven innings while allowing three earned runs in his last start. Both pitchers are performing at a high level and will be one of the keys to the outcome in Cincinnati tonight.

Key Players

  • George Springer (TOR): Springer is leading the Blue Jays with 26 homers and he continues to anchor the powerful Blue Jays offense.
  • Bo Bichette (TOR): Bichette enters this game with a .310 average and 91 RBI.
  • Elly De La Cruz (CIN): De La Cruz is a rising star and leads the Reds in both home runs and RBI.

Recent team streaks

  • The Blue Jays rebounded from a loss in the opening game of this series with a resounding 12–9 win on Tuesday. They have won two of their last three games.
  • Cincinnati saw a two-game winning streak come to an end with their loss to the Jays last night.

Best Player Props

PlayerSuggested Prop
George Springer (TOR)Over 0.5 HR
Shane Bieber (TOR)Over 5.5 Ks
Bo Bichette (TOR)Under 1.5 TB
  • The Blue Jays and Reds are 1-1 against each other so far this season.
  • This is the final game scheduled between Toronto and Cincinnati this year.
  • Both games in this three-game series have gone over their respective totals. Tuesday’s game was especially high-scoring with 21 runs between the two teams.

Blue Jays vs Reds Model Projection

Score Projection: Reds 6 – Blue Jays 5

Win Probability: Blue Jays 50%, Reds 50%

Final Thoughts

This game is a lot more evenly matched than the odds would imply as far as I’m concerned. The Reds have an explosive offense that can keep up with that of Toronto. And Toronto has been aggressively mediocre on the road this season, which I think will continue here. I’ll go with the Reds to win this game as an underdog at home.


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Home MLB Picks Toronto Blue Jays vs Cincinnati Reds Pick – 9/3/2025