The Texas Rangers and Houston Astros will wrap up their three-game series at Daikin Park on Wednesday night. The Astros have come through with wins in the first two games of this series and will look to secure an important sweep with a win tonight. But they will need to overcome one of the best pitchers in baseball to accomplish that. Here, I break down this MLB matchup and give you my Rangers vs Astros prediction for Wednesday’s game.
Our Rangers vs Astros Pick
- Pick: Texas Rangers moneyline
- Confidence: 5/5
- Get Your Bonus Bets: Click the Claim Bonus button to grab our DraftKings Sportsbook promo and bet $5 to win $200 in bonus bets INSTANTLY for this game!
Bet $5, Get $200 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $200 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Teams: Texas Rangers vs Houston Astros
- Date & Time: Wednesday, September 17, 2025, 8:10 PM ET
- Starting Pitchers: Jacob deGrom vs Cristian Javier
- Stadium: Daikin Park, Houston, TX
- Broadcast: MLB.tv
Key Storylines
- The Astros are within a half-game of the Seattle Mariners in the AL West standings after winning the first two games of this series. Houston is also sitting in the third AL Wild Card position and will look to help their chances in both of those races with another win tonight.
- The Rangers have dropped to 3.5 games back of the final AL Wild Card spot. Their inability to grab games early in this series has cost them dearly going into their final matchup against the Astros for the season.
- Yordan Alvarez is out with a sprained ankle and losing him will be devastating for the Houston lineup going into the stretch run.
Pitching Outlook
Jacob deGrom has delivered ace-level run prevention this season. He comes into this start with a 2.82 ERA, a sub-1.00 WHIP, and 171 strikeouts. His fastball-slider combo has looked crisp in September, and he just logged a 7-inning gem in New York that featured elite command against his former team. The Rangers absolutely need a gem from deGrom tonight.
Houston will go with Cristian Javier on the mound for this huge game. Javier is 1-3 this season and has a 4.78 ERA. He is certainly the second-best starting pitcher on paper going into this game. But a strong outing from Javier could elevate the Astros and crush the playoff hopes of the Rangers.
Recent Team Streaks
- The Rangers have lost three games in a row at the worst possible time this season.
- Houston has won two straight games and four of their last five.
Best Player Props
- Jacob deGrom Over 7.5 Strikeouts
- Jose Altuve Over 0.5 Home Runs
- Jeremy Pena over 1.5 Total Bases
- Cristian Javier Under 4.5 Strikeouts
Betting Trends & H2H
- The Rangers and Astros are tied 6-6 in their regular-season series.
- Houston has won three of their last four meetings against the Rangers.
- This is the final game of the regular-season series between these two teams.
Rangers vs Astros Model Projection
Score Projection: Texas 4 – Houston 2
Win Probability: Texas 58%, Houston 42%
Final Thoughts
The Rangers have exactly the pitcher they need on the mound for a must-win game tonight. Jacob deGrom should deliver in a big way in this contest and the Rangers should get a win that they need to avoid falling even further behind in the AL Wild Card race. I’ll take the Rangers to win on the moneyline and for Texas to win their season series over Houston.
