Tampa Bay Rays vs San Francisco Giants Pick – 8/16/2025

The Tampa Bay Rays and San Francisco Giants are set to face off on Saturday night at Oracle Park in San Francisco. Both teams are currently on the fringes of playoff contention and will look for a win to help their Wild Card chances here. The Rays won an exciting series opener against the Giants on Friday. Before they play for the second time, continue reading to get my Rays vs Giants prediction.

Our Rays vs Giants Pick

  • Pick: Tampa Bay Rays Moneyline
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: Tampa Bay Rays vs San Francisco Giants
  • Date & Time: Saturday, August 16, 2025, 9:05 PM ET
  • Starting Pitchers: Adrian Houser (TB) vs Justin Verlander (SF)
  • Stadium: Oracle Park, San Francisco, CA
  • Broadcast: NBC Sports Bay Area, FDSN Sun

Key Storylines

Pitching Matchup

Adrian Houser has posted a 6–4 record with a 2.84 ERA and 1.32 WHIP this season. But Houser has struggled in his two starts with the Rays. He has allowed nine earned runs over 10.2 innings since coming over from the Chicago White Sox. But he has a strong history against the Giants after throwing seven scoreless innings against them in June. Justin Verlander has had a challenging season with a 1–9 record and a 4.53 ERA. He most recently allowed five earned runs in an 8–0 loss to the Nationals.

Key Players

  • Junior Caminero (TB): The Rays’ slugger hit his 35th home run of the season in last night’s win for the Rays.
  • Yandy Diaz (TB): Diaz had two RBI for the Rays last night and will look to make an impact on this game as well.
  • Willy Adames (SF): The former Ray is now with the Giants. He hit a home run against his former team in last night’s loss.
  • Heliot Ramos (SF): Ramos had an RBI double and his ability to generate extra-base hits will be key in this game as well.

Recent Team Streaks

The Rays have won three of their last four games and got their second win in a row last night. The Giants dropped their sixth consecutive game in their loss on Friday.

Best Player Props

PlayerProp
Junior CamineroOver 0.5 Home Runs
Jonathan ArandaOver 1.5 Total Bases
Justin VerlanderUnder 5.5 Strikeouts
  • The Rays won the only game played between these teams this season last night.
  • The first game of this series saw 13 total runs scored and the game flew over the total.

Rays vs Giants Model Projection

  • Score Projection: Rays 5 – Giants 4
  • Win Probability: Rays 57.77%, Giants 42.23%

Final Thoughts

The Rays should have the upper hand against the Giants again on Saturday night. Justin Verlander has not been the pitcher the Giants hoped he would be this year. That should continue in this game and I expect Houser to outclass him early in this game. I’ll take the Rays to win a second straight in San Francisco here.


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Home MLB Picks Tampa Bay Rays vs San Francisco Giants Pick – 8/16/2025