St. Louis Cardinals vs San Diego Padres Prediction – 8/3/2025
The St. Louis Cardinals will face off against the San Diego Padres on Sunday afternoon at Petco Park. These teams have been evenly matched this weekend and in their season series as a whole. But this game will break the deadlock between them in their final meeting of 2025. Continue reading to find out who I like in this matchup as I bring you my Cardinals vs Padres prediction for Sunday’s matchup.
Our Cardinals vs Padres Pick
- Pick: Cardinals to win
- Confidence: ★★★★☆
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Game Snapshot
- Matchup: St. Louis Cardinals vs San Diego Padres
- Date & Time: Sunday, August 3, 2025, 4:10 PM EDT
- Starting Pitchers: Andre Pallante (STL) vs Dylan Cease (SD)
- Stadium: Petco Park, San Diego, CA
- Broadcast: Padres Television Network, FanDuel Sports Network Midwest
Key Storylines
Pitching Matchup
- Andre Pallante (STL): 6-7, 4.62 ERA, 1.31 WHIP, 76 SO
- Dylan Cease (SD): 3-10, 4.79 ERA, 1.34 WHIP, 153 SO
Pallante has shown improvement recently. He earned a win in his last start with seven scoreless innings. Cease has a high ERA but is one of the best in the league when it comes to strikeouts per nine innings. Whichever starter has the better day here will give their team a huge lift.
Key Players
- Willson Contreras (STL): 15 HR, .257 AVG, 63 RBI
- Alec Burleson (STL): .284 AVG, .341 OBP, .463 SLG
- Manny Machado (SD): 20 HR, .301 AVG, 72 RBI
- Fernando Tatis Jr. (SD): .264 AVG, 17 HR, 44 RBI
Contreras and Burleson provide the offensive spark for the Cardinals and will look to keep doing so in this game. Machado and Tatis offer consistent power and run production for the Padres.
Recent Team Streaks
- Cardinals: St. Louis snapped a three-game losing streak with their win in San Diego on Saturday.
- Padres: San Diego had a six-game winning streak snapped when they lost to the Cards in their last outing.
Best Player Props
| Player | Prop |
|---|---|
| Willson Contreras | Over 0.5 HR |
| Manny Machado | Over 0.5 HR |
| Dylan Cease | Over 7.5 Strikeouts |
Betting Trends & H2H
- Cardinals: 24-32 away record
- Padres: 35-19 home record
- These teams are tied 3-3 in their season series this year. The winner of this game will clinch the regular-season series between them.
The Padres have a significant advantage at home this season. But they are not infallible at home, as we saw on Saturday.
Cardinals vs Padres Model Projection
- Score Projection: Cardinals 5 – Padres 4
- Win Probability: Cardinals 50%, Padres 50%
Final Thoughts
Dylan Cease has some impressive strikeout numbers. But his overall body of work is not nearly as impressive when you peel back a few layers. I think this game is a toss-up and I will take the Cardinals at plus money in a game that could go in either direction on Sunday afternoon.
