St. Louis Cardinals vs Los Angeles Dodgers Pick – 8/6/2025
The Los Angeles Dodgers will host the St. Louis Cardinals on Wednesday afternoon at Dodger Stadium. The Dodgers roared back to even this three-game series at a game apiece with a late offensive barrage on Tuesday night. They will look to secure the series win at home with their best player on the mound. Continue reading to get a full breakdown of this game, including my Cardinals vs Dodgers prediction.
Our Cardinals vs Dodgers Pick
- Pick: Los Angeles Dodgers -1.5
- Confidence: 4 stars
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Game Snapshot
- Matchup: St. Louis Cardinals vs. Los Angeles Dodgers
- Date & Time: Wednesday, August 6, 2025, 4:10 PM ET
- Starting Pitchers: Matthew Liberatore (STL) vs. Shohei Ohtani (LAD)
- Stadium: Dodger Stadium, Los Angeles, CA
- Broadcast: MLB Network
Key Storylines
Pitching Matchup
Matthew Liberatore will take the mound for the Cardinals. He is 6-9 and has a solid 3.52 ERA over 21 starts this season. His ability to keep hitters off balance with a mix of fastballs and off-speed pitches has been a strength. But even the best starting pitchers have a tendency to struggle against the potent lineup of the Dodgers and that could happen again here.
Shohei Ohtani is set to make his return to the mound after a brief exit in his previous start due to right hip cramps. Ohtani has yet to register a win or a loss on the mound this season. He has a 2.40 ERA in 15 innings and the Dodgers have been very cautious with him since his return to pitching.
Key Players
- Freddie Freeman (LAD): Freeman drove in a couple of runs last night on sacrifice flies and his savvy at the plate is always helpful to the Dodgers.
- Mookie Betts (LAD): Betts went 3-4 last night for Los Angeles and scored three runs.
- Max Muncy (LAD): Muncy went 4-5 and had two home runs to propel the Dodgers to a 12-6 win on Tuesday.
- Lars Nootbaar (STL): If anyone is going to step up and provide some support for Willson Contreras in the Cardinals’ lineup, I think it will be Nootbaar.
Recent Team Streaks
- The Dodgers have won three of their last five games. They have covered the runline in those three wins.
- The Cardinals have lost three of their last five games against the Dodgers and the San Diego Padres.
Best Player Props
| Player | Prop |
|---|---|
| Freddie Freeman | Over 0.5 Home Runs |
| Mookie Betts | Over 1.5 Total Bases |
| Lars Nootbaar | Over 0.5 Home Runs |
Betting Trends & H2H
- The Cardinals lead the season series between these teams 3-2.
- This is the final regular season meeting scheduled for these two teams in 2025.
- The under is 3-2 in games played between the Cardinals and Dodgers.
Cardinals vs Dodgers Model Projection
- Score Projection: Cardinals 3 – Dodgers 5
- Win Probability: Cardinals 40%, Dodgers 60%
Final Thoughts
The hope in this game would be for Shohei Ohtani to take the mound for more than just a couple of innings. But the Dodgers should have the upper hand no matter how long Ohtani starts for. Los Angeles’ offense is operating at a high level and I will lay the runline with LA in this game.
