St. Louis Cardinals vs Colorado Rockies Prediction – 7/23/2025
The St. Louis Cardinals close out their three‑game series in Denver against the struggling Colorado Rockies on Wednesday. The Cardinals are the favorites going into this matchup. But they have split the first two games of this series with the Rockies. Before this rubber match gets going from Colorado, continue reading to get my Cardinals vs Rockies prediction for today.
Our Cardinals vs Rockies Pick
Pick: Cardinals moneyline
Confidence: ★★★★☆
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The Rockies have struggled all season, posting a 25–76 record and going 13–38 at home.
Andre Pallante’s been streaky this year for the Cardinals. But his team is 3–2 in his last five starts and he will look to give them the upper hand here as well.
St. Louis won the opener 6–2 and dropped Game 2 by a score of 8–4. They are 1-1 as favorites in this series thus far.
Colorado’s starter is yet to be announced. We could see them go with their bullpen for a full nine innings today. That would be troubling given that they 27th in the league in bullpen ERA.
The Cardinals have lost four of their last five games coming into this contest. Colorado snapped a two-game losing streak with a win over the Cardinals on Tuesday.
Best Player Props
Player
Prop
Andre Pallante
Over 4.5 Strikeouts
Hunter Goodman
Over 1.5 Total bases
Betting Trends & H2H
The season series between these teams is tied 1-1.
After this game, these teams will have another three-game series against each other in mid-August.
The Cardinals are 24-24 in day games this season. The Rockies are 12-29 in day games.
Cardinals vs Rockies Model Projection
Score Projection: Cardinals 6 – Rockies 3
Win Probability: Cardinals 62% – Rockies 38%
Final Thoughts
St. Louis enters this game with clear advantage in pitching and run creation. Andre Pallante should be more stable than the Rockies bullpen in the early stages of this game. I think that Pallante will help the Cardinals get out to an early lead and that the St. Louis bullpen will do enough down the stretch to help Pallante get the win.
Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.
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Affiliate Disclosure ATS.io features affiliate links to licensed online casinos, sportsbooks, and gambling platforms. That means if you click on them and end up signing up or making a deposit, we might earn a commission at no extra cost to you. We only work with licensed and reputable online casinos, social casinos and sportsbooks. Our content whether it’s reviews, guides, or betting tips is written with the goal of being honest, helpful, and based on real experience. While we do earn through affiliate partnerships, it doesn’t affect our recommendations. If a site isn’t safe or doesn’t meet our standards, we won’t promote it. Simple as that. We also take responsible gambling seriously. We encourage all our readers to gamble safely, set limits, and know when to take a break. Have questions? Feel free to reach out. We’re always happy to chat.
Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.
Home›MLB Picks›St. Louis Cardinals vs Colorado Rockies Prediction – 7/23/2025
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