St. Louis Cardinals vs Cincinnati Reds Prediction – 8/30/2025

The St. Louis Cardinals will visit the Cincinanti Reds on Saturday night at Great American Ball Park. St. Louis took the first game of this three-game set on the road. But they will face a tough test against one of the best starting pitchers in the National League in this game. Before these NL Central rivals face off, continue reading to get my Cardinals vs Reds prediction.

Our Cardinals vs Reds Pick

  • Pick: Cincinnati Reds moneyline
  • Confidence: 4/5
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Game Snapshot

  • Matchup: St. Louis Cardinals at Cincinnati Reds
  • Date & Time: Saturday, August 30, 2025, 6:40 PM ET
  • Starting Pitchers: Michael McGreevy vs Andrew Abbott
  • Stadium: Great American Ball Park, Cincinnati, OH
  • Broadcast: MLB.tv

Key Storylines

  • Cincinnati needs a bounce back after a losing skid and will lean on ace Andrew Abbott to steady the ship.
  • The Cardinals are still 6.5 games back in the NL Wild Card race and they need to keep stacking up wins.
  • Cincinnati is the last team out of the Wild Card race in the NL and they are also looking for wins to help them catch up.

Pitching matchup

Andrew Abbott has been Cincinnati’s ace this season with an 8-4 record and a 2.62 ERA. He has 118 strikeouts and a 1.10 WHIP across about 134 innings. He induces weak contact, racks up whiffs, and limits hard contact more often than not. Michael McGreevy has a 5-2 record and an ERA in the mid 4.00s for the Cardinals this year. Abbott offers a clear edge in starting pitching for the Reds in this game and the question will be whether that is enough for them to get the win.

Recent team streaks

  • The Reds have dropped four games in a row coming into this matchup with the Cardinals.
  • St. Louis has won two straight games and three of their last five.

Best Player Props

PlayerProp
Elly De La CruzOver 1.5 Total Bases
Andrew AbbottOver 5.5 Strikeouts
Michael McGreevyUnder 4.5 Strikeouts
  • The Cardinals have a 5-3 lead in the season series against the Reds this year.
  • The first game of this three-game series went over the total on Friday night.
  • St. Louis has won three of the last four games between these teams.

Cardinals vs Reds Model Projection

Score Projection: Cincinnati 5 – St. Louis 3

Win Probability: Cincinnati 62%, St. Louis 38%

Final Thoughts

The Reds are an easy choice to back in this game. They are at home and have had success at Great American Ball Park in 2025. They also have their best pitcher on the mound in Andrew Abbott. I’ll take the Reds to win this game convincingly, as they should get out to an early lead with Abbott on the hill and coast to victory from there.


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