San Francisco Giants vs Milwaukee Brewers Pick – 8/23/2025

The Milwaukee Brewers will take on the San Francisco Giants on Saturday night at American Family Field in Milwaukee. Milwaukee enters this game with the best record in baseball and off a win over the Giants in the opening game of the series. The Brew Crew will look to continue their winning ways at home here at the expense of a Wild Card hopeful in the Giants. Continue reading to get my Brewers vs Giants prediction for Saturday night.

Our Brewers vs Giants Pick

  • Pick: Brewers Moneyline
  • Confidence: 4/5
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Game Snapshot

  • Matchup: San Francisco Giants at Milwaukee Brewers
  • Date & Time: Saturday, August 23, 2025, 7:10 p.m. ET
  • Starting Pitchers: Freddy Peralta (MIL) vs Logan Webb (SF)
  • Stadium: American Family Field, Milwaukee, WI
  • Broadcast: FDSWI and NBCS-BA

Key Storylines

Pitching matchup

Freddy Peralta has been dominant in 2025 with a 15-5 record and a 2.78 ERA. He has thrown six scoreless innings in each of his last two starts. Peralta will look to deliver again for the Brewers in this start against San Francisco. Logan Webb is also a consistent performer for the Giants. He enters this start with a 3.19 ERA and a 1.22 WHIP. He has a perfect 3-0 record against Milwaukee with a 2.17 ERA in those outings.

Key Players

William Contreras hit a walk-off home run for the Brewers in the ninth inning of Friday’s win over the Giants. Contreras will be a key figure for the Brewers offensively in this game as well. Willy Adames will be a key contributor for the Giants after his two-home run performance that helped the Giants hang around in Friday’s loss.

Recent team streaks

The Brewers are riding a seven-game home win streak and they have won two straight games overall. The Giants have lost four straight games and are falling further behind in the NL Wild Card race at this stage of the season.

Best Player Props

PlayerStatProp
Christian YelichHome RunsOver 0.5
Logan WebbStrikeoutsUnder 5.5
William ContrerasTotal BasesOver 1.5
  • The Giants lead the season series 3-2 against the Brewers this year.
  • Milwaukee is tied for the third-best runline record in MLB this year at 74-55.
  • Both teams have gone under the total in the majority of their games this season.

Giants vs Brewers Model Projection

Score Projection: Brewers 5 – Giants 2

Win Probability: Brewers 62%, Giants 38%

Final Thoughts

Milwaukee is simply operating on a higher level than the Giants at this point in time. Nothing is ever a certainty in baseball, and Logan Webb is a very good starting pitcher for the Giants, but the Brewers are playing so well that I have to back them to win this game. We should see Peralta win his 16th game of the season in another victory at home for the Brew Crew.


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Home MLB Picks San Francisco Giants vs Milwaukee Brewers Pick – 8/23/2025