San Francisco Giants vs Athletics Prediction – 7/5/2025

The San Francisco Giants and the Athletics will meet tonight at Sutter Health Park in Sacramento for Game 2 of their interleague series. The A’s dominated the first game of this series on Friday, scoring 11 runs against Justin Verlander and the Giants. Here, I make my Giants vs Athletics prediction as the Giants look to even this series up at a game apiece.

Our Giants vs Athletics Pick

  • Pick: Giants moneyline
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: San Francisco Giants vs Oakland Athletics
  • Date & Time: Saturday, July 5, 2025 at 10:05 PM EDT
  • Starting Pitchers: Logan Webb (SF) vs Luis Severino (OAK)
  • Stadium: Sutter Health Park, West Sacramento, CA
  • Broadcast: NBCS‑CA and NBCS‑BA

Key Storylines

Pitching Form

Logan Webb will get the start for the Giants in this game. Webb is 7-6 with a 2.61 ERA and I project him to give the Giants a better chance to win tonight than Verlander did yesterday. Webb will be opposed by Luis Severino. Severino is 2-9 this season with a 5.09 ERA and he needs to be sharper if he is going to get a win for his team tonight.

Bullpen Usage

San Francisco’s bullpen is elite, with the best ERA in MLB at 2.99. The Athletics rank 29 out of 30 MLB teams in bullpen ERA at 5.78, which will be especially problematic if Severino can’t last deep into this game.

Recent Team Streaks

  • The Giants had a two-game winning streak snapped by the A’s last night.
  • The Athletics have won three of their last four games.

Best Player Props

PlayerPropOdds
Rafael Devers (SF)Home runs over 0.5+255
Logan Webb (SF)Strikeouts over 6.5–140
Jacob Wilson (OAK)Total bases over 1.5+100
  • The Giants are 3-1 against the Athletics so far this season.
  • The A’s have gone over the total in 56% of their games this season, ranking third in the league.
  • The Giants have covered the runline in just 43.8% of their games, the fifth-worst number in MLB.

Giants vs Athletics Model Projection

Score Projection: Giants 5 – Athletics 3

Win Probability: Giants 63%, Athletics 37%

Final Thoughts

The Giants have had trouble covering the runline throughout the 2025 MLB season. But I am going to take them to do just that in this game. San Francisco has a major pitching advantage in this contest with Webb taking on Severino. I expect that to help the Giants grab the lead, and for their superior bullpen to help them keep it throughout.


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Home MLB Picks San Francisco Giants vs Athletics Prediction – 7/5/2025