San Francisco Giants vs Arizona Diamondbacks Pick – 7/1/2025

Tuesday night’s showdown at Chase Field between the San Francisco Giants and Arizona Diamondbacks will be an intriguing National League West duel. The Diamondbacks, holding a 42‑42 record, look to seize the series after beating the Giants in the opener. San Francisco brings a 45‑40 record, riding on solid pitching and seeking to shake off a rough stretch that’s seen them lose six of seven. Here, I will break down this game between division rivals and make my Giants vs Diamondbacks prediction.

Our Giants vs Diamondbacks Prediction

Pick: San Francisco Giants moneyline

Confidence: ★★★★☆

Game Snapshot

• Matchup: San Francisco Giants vs Arizona Diamondbacks
• Date & Time: Tuesday, July 1, 2025 – 9:40 PM ET
• Starting Pitchers: Hayden Birdsong (SF, 3‑2, 4.13 ERA) vs Zac Gallen (ARI, 5‑9, 5.75 ERA)
• Stadium: Chase Field, Phoenix, AZ
• Broadcast: ARIZONA-FAST, NBCS-BA

Key Storylines

Pitching Form

• Zac Gallen continues to struggle with a 5.75 ERA and 1.41 WHIP in 17 starts, allowing four or more earned runs nearly half the time.
• Hayden Birdsong, in contrast, has delivered nine outings with zero earned runs and two in which he gave up three or fewer runs, posting a respectable 4.13 ERA.

Bullpen Usage

The Giants’ relief corps ranks among MLB’s best (3.39 ERA) and should thrive in the later innings. The Diamondbacks’ bullpen is less efficient, especially when Gallen departs early.

Recent Team Streaks

• Giants have lost 6 of 7 games and are 1‑4 SU on the road versus Arizona.
• Arizona snapped a four-game skid in Monday’s win but remains near .500 overall at home.

Best Player Props

Betting Trends & H2H

• Last 5 games: Arizona 1‑4 SU, San Francisco 1‑4 SU.
• Arizona is 21-21 at home this season, Giants are 20-23 on the road.

San Francisco Giants vs Arizona Diamondbacks Model Projection

Score Projection: San Francisco 4 – Arizona 3

Win Probability: San Francisco 47%, Arizona 53%

Final Thoughts

Despite Arizona’s home advantage, Gallen’s season-long struggles and command issues shift the margin toward San Francisco in my eyes. The Giants’ bullpen and Birdsong’s steady outings provide a foundation the offense can build on. While Arizona remains favored, the underdog value on the Giants with a moneyline edge at +115 offers compelling upside. I expect a game where clutch pitching and late-inning relief could tip the scales in San Fran’s favor.

Affiliate Disclosure

ATS.io features affiliate links to licensed online casinos, sportsbooks, and gambling platforms. That means if you click on them and end up signing up or making a deposit, we might earn a commission at no extra cost to you. We only work with licensed and reputable online casinos, social casinos and sportsbooks. Our content whether it’s reviews, guides, or betting tips is written with the goal of being honest, helpful, and based on real experience. While we do earn through affiliate partnerships, it doesn’t affect our recommendations. If a site isn’t safe or doesn’t meet our standards, we won’t promote it. Simple as that. We also take responsible gambling seriously. We encourage all our readers to gamble safely, set limits, and know when to take a break. Have questions? Feel free to reach out. We’re always happy to chat.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.