San Diego Padres vs San Francisco Giants Prediction – 8/12/2025

The San Diego Padres will visit the San Francisco Giants at Oracle Park on Tuesday night. The Padres managed to get the better of Giants ace Logan Webb on Monday night. San Diego will look for a second straight win and San Francisco will look to snap their losing streak and get back to .500 for the season. Here, I give you my breakdown of this key NL West game, including my Padres vs Giants prediction.

Our Padres vs Giants Pick

  • Pick: Giants ML
  • Confidence: 3/5 stars
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Game Snapshot

  • Matchup: San Diego Padres vs. San Francisco Giants
  • Date & Time: Tuesday, August 12, 2025, 9:45 PM EDT
  • Starting Pitchers: Nestor Cortes (Padres) vs. Robbie Ray (Giants)
  • Stadium: Oracle Park, San Francisco, CA
  • Broadcast: NBCS-BA, Padres Television Network

Key Storylines

Pitching Matchup

Nestor Cortes makes his second start for the Padres after a solid debut. He allowed two runs over 4.2 innings against Arizona in his debut with the Padres. His ERA stands at 7.11 but Cortes is more than capable of showing his old form in this game.

Robbie Ray has a 9–5 record with a 2.85 ERA and 148 strikeouts for the Giants. But he has been winless in his last six starts. That may indicate some underlying issues despite his impressive numbers for the season overall.

Key Players

  • Manny Machado (Padres): Leading the Padres with 20 home runs and 72 RBI. Machado’s bat is crucial to the team’s success.
  • Willy Adames (Giants): Adames provides power in the middle of the Giants’ lineup with 18 home runs and 61 RBI.

Recent Team Streaks

  • The Giants have lost three games in a row and four of their last five.
  • The Padres have won three games in a row going into this matchup.

Best Player Props

PlayerProp
Manny MachadoOver 0.5 Home Runs
Willy AdamesOver 0.5 Home Runs
Dominic SmithOver 0.5 Home Runs
  • The Padres have a 5-2 lead in the season series against the Red Sox.
  • The Giants have scored three total runs over their last three games.
  • The last two games between these teams have gone under the total.

Padres vs Giants Model Projection

  • Score Projection: Giants 4 – Padres 3
  • Win Probability: Giants 52%, Padres 48%

Final Thoughts

I’m expecting both starting pitchers in this game to step up relative to what we have seen from them lately. Both Cortes and Ray have strong starts in them at this stage of their careers and should show that tonight. As for who wins this game, I will go with the Giants to end their losing streak with a win at home thanks to the superior pitching of Robbie Ray.


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