Pittsburgh Pirates vs San Francisco Giants Prediction – 7/29/2025

The Pittsburgh Pirates will face the San Francisco Giants in a National League matchup on Tuesday night. The Pirates shocked the Giants in San Francisco on Monday and will look for another win over their Bay Area adversaries here. Before first pitch from San Francisco, continue reading to get my Pirates vs Giants prediction for this one.


Our Pirates vs Giants Pick

  • Pick: Pirates Moneyline
  • Confidence: ★★★★☆
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Game Snapshot

MatchupPittsburgh Pirates vs. San Francisco Giants
Date & TimeJuly 29, 2025, 9:45 p.m. ET
Starting PitchersBailey Falter vs. Justin Verlander
StadiumOracle Park, San Francisco, CA
BroadcastMLB Network

Key Storylines to Watch

  • Pitching Form: Pittsburgh has Bailey Falter on the mound for this contest. Falter is 7-5 with a 3.82 ERA. Like Paul Skenes, Falter would have a better record if he got more run support from the Pirates lineup. San Francisco will throw Justin Verlander in this matchup. Verlander is 1-8 this season with a 4.70 ERA and is clearly not the same pitcher he used to be.

  • Bullpen Usage: The Giants have the third-best bullpen ERA in baseball this year. But they fell short with their relief pitching in their loss to the Pirates on Monday.

  • Team Momentum: Pittsburgh has won three straight games and four of its last five. The Giants have lost four games in a row after dropping their series opener against the Pirates.


Best Player Props

PlayerPropPick
Oneil CruzTotal BasesOver 1.5
Oneil CruzHome RunsOver 0.5

  • The Pirates won the first game of the season series between these teams 6-5.

  • The first game of this series went over the total with 11 total runs scored.

  • San Francisco enters this game at 54-53 for the season. They will look to stay above the .500 mark with a win.

  • The Pirates have allowed one or fewer runs in four of their last five games.


Pirates vs Giants Model Projection

Projected Score: Pirates 5 – Giants 4
Win Probability: Pirates 53% | Giants 47%


Final Thoughts

The Pittsburgh Pirates are playing some of their best baseball of the season lately. They have one of their best pitchers on the mound tonight in Falter as well. I expect the Pirates to prolong the struggles of the Giants in this matchup, despite the bullpen advantage the Giants have in their favor. I’ll go with the Pirates to win at plus money tonight behind a solid showing from Falter.


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Home MLB Picks Pittsburgh Pirates vs San Francisco Giants Prediction – 7/29/2025