Pittsburgh Pirates vs Milwaukee Brewers Prediction – 8/12/2025
The Milwaukee Brewers come into Tuesday night on a 10-game winning streak. But they will be put to the test by Paul Skenes and the Pittsburgh Pirates at American Family Field in this game. Skenes is the frontrunner to win this year’s NL Cy Young and will look to shut down one of the hottest teams in baseball here. Continue reading to get my thoughts on this matchup and to get my Pirates vs Brewers prediction for the night.
Our Pirates vs Brewers Pick
- Pick: Milwaukee Brewers moneyline
- Confidence: 4/5
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Game Snapshot
- Matchup: Pittsburgh Pirates at Milwaukee Brewers
- Date & Time: Tuesday, August 12, 2025, 7:40 p.m. ET
- Starting Pitchers: Paul Skenes vs Freddy Peralta
- Stadium: American Family Field, Milwaukee, WI
- Broadcast: FDSWI and SportsNet PT
Key Storylines
Pitching matchup
Paul Skenes was last season’s NL Rookie of the Year and has elevated his game in 2025. He enters with a 1.94 ERA and 162 strikeouts over 144 innings. Skenes is leading the league in ERA and FIP. He blanked the Reds in his last outing over six scoreless innings and has a strong 2.65 ERA against Milwaukee in three career starts. Freddy Peralta leads MLB with 13 wins for the Brewers. He has a 3.03 ERA and 141 strikeouts.
Key Players
The lineup of the Brewers in its entirety will be the key players in this game. The goal for them will be to drive up Skenes’ pitch count in this game. The sooner Skenes is off the mound, the better things will go for the Brewers offensively and every single hitter will need to contribute to driving that pitch count up.
Recent team streaks
The Brewers have won 10 straight and are dominant at home. Pittsburgh has lost three games in a row and will look to end that streak in this matchup of the first and last place teams in the NL Central.
Best Player Props
| Player | Prop Type | Projection |
|---|---|---|
| Christian Yelich | Home runs | Over 0.5 HR |
| Paul Skenes | Strikeouts | Under 7.5 Ks |
| William Contreras | Total bases | Over 1.5 TB |
Betting Trends & H2H
- The Brewers lead the season series between these teams 5-3.
- Milwaukee has the best record in baseball at 74-44.
- The Brewers improved to 40-20 at home with their win on Monday.
Pirates vs Brewers Model Projection
Score Projection: Brewers 5 – Pirates 3
Win Probability: Brewers 60%, Pirates 40%
Final Thoughts
This could be Pittsburgh’s best chance to snag a road win this week with Skenes on the mound. But I don’t think Skenes will be enough to derail the red-hot Brewers at this point in time. Skenes has a losing record this season despite how great he has been on the hill. That is a sign that the team around him is not good enough and that should continue to be the case tonight.
