Pittsburgh Pirates vs Milwaukee Brewers Pick – 8/13/2025

The Milwaukee Brewers put a hurting on the Pittsburgh Pirates on Tuesday night. Pittsburgh had Paul Skenes on the mound in that game but couldn’t stop an offensive onslaught by the Brewers. Milwaukee will look for another convincing victory over the Pirates on Wednesday afternoon. Before that game begins, you can keep reading to get my Pirates vs Brewers prediction.

Our Pirates vs Brewers Pick

  • Pick: Brewers -1.5
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Pittsburgh Pirates vs Milwaukee Brewers
  • Date & Time: Wednesday, August 13, 2025, 2:10 PM EDT
  • Starting Pitchers: Mitch Keller (5-10, 3.86 ERA) vs Brandon Woodruff (4-0, 2.29 ERA)
  • Stadium: American Family Field, Milwaukee, WI
  • Broadcast: MLB Network

Key Storylines

  • The Milwaukee Brewers extended their winning streak to 11 games on Tuesday night and will look to stay hot with a win at home here.
  • The Brewers completely blew the Pirates out on Tuesday. Milwaukee won that game 14-0 in a score that looked more like a game between the Packers and Steelers than the Brewers and Pirates.

Pitching Matchup

Brandon Woodruff has been great with a 2.29 ERA and spotless 4-0 record this season. His six starts have all ended in wins. He has a 3.40 career ERA over 17 starts against the Pirates and will look to beat them again here. Pittsburgh’s Mitch Keller enters with a 3.86 ERA and 1.23 WHIP on the season. He has struggled on the road and will need to tighten things up away from PNC Park to contend with Woodruff.

Key Players

  • Christian Yelich had three RBI for the Brewers in their 14-0 win over Pittsburgh. His two-run home run in the fifth inning helped to break the game open.
  • Sal Frelick leads the Brewers in batting average and he knocked in two runs for Milwaukee on Tuesday.
  • The Pittsburgh bullpen will be a key to this game. After they took a beating on Tuesday they need to regain some confidence while dealing with possible fatigue.

Recent Team Streaks

  • Milwaukee enters on an 11-game winning streak and has the best record in baseball.
  • Pittsburgh has lost four games in a row and is looking to bounce back from a humiliating defeat.

Best Player Props

PlayerProp
Christian Yelich (MIL)Over 0.5 Home Runs
William Contreras (MIL)Over 1.5 Total Bases
  • The Brewers lead the season series against the Pirates 6-3.
  • Pittsburgh is 28-41 after a loss this season.
  • Milwaukee has won four straight games over the Brewers heading into Wednesday’s play.

Pirates vs Brewers Model Projection

Score Projection: Pirates 3 – Brewers 5

Win Probability: Pirates 35 %, Brewers 65 %

Final Thoughts

I’m not sure how you can pick against the Milwaukee Brewers right now. Milwaukee is on fire and they are making it clear that they could be the best team in baseball. I will take the Brewers to win this game behind Woodruff. The Brew Crew will cover the runline and hand the Pirates yet another loss on the road.


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Home MLB Picks Pittsburgh Pirates vs Milwaukee Brewers Pick – 8/13/2025