Pittsburgh Pirates vs Chicago Cubs Prediction – 8/17/2025

The Pittsburgh Pirates and Chicago Cubs will wrap up a three-game weekend series against each other on Sunday afternoon. Both teams have taken one game to start this series from Wrigley Field. The winner of this game will claim this three-game set and have some positive momentum going into their next series. Before this game begins from the Windy City, you can find my Pirates vs Cubs prediction below.

Our Pirates vs Cubs Pick

  • Pick: Over 7.5
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Chicago Cubs vs Pittsburgh Pirates
  • Date & Time: Sunday, August 17, 2025, 2:20 p.m. ET
  • Starting Pitchers: Javier Assad (0–1, 9.00 ERA) vs Carmen Mlodzinski (2–7, 4.20 ERA)
  • Stadium: Wrigley Field, Chicago, IL
  • Broadcast: MARQ and SportsNet PT

Key Storylines

Pitching matchup

Javier Assad will get the start on Sunday for the Cubs. His last appearance on August 12 saw him allow four runs and eight hits over four innings. He looked good in his rehab assignments but struggled in his return to the majors. Assad will look to rebound in this series finale.

Carmen Mlodzinski will get the ball for the Pirates. He enters this one at 2–7 with a 4.20 ERA. Mlodzinski has a 1.39 WHIP. That number is far from ideal but looks great compared to Assad’s WHIP over a small sample size.

Playoff Situation

The Chicago Cubs are sitting at the top of the National League Wild Card standings. The Cubbies have fallen way behind the Milwaukee Brewers in the NL Central standings. That likely leaves the Cubs with a Wild Card spot to play for. As long as they don’t collapse over the next six weeks, it would be hard for Chicago to miss the playoffs.

Recent team streaks

The Cubs are 2-3 in their last five games but they did beat the Pirates on Saturday afternoon. Pittsburgh has lost four of its last five games and are in last place in the NL Central.

Best Player Props

CategoryPlayerProp
Home runsSeiya SuzukiOver 0.5
StrikeoutsJavier AssadUnder 5.5
Total basesKyle TuckerOver 1.5
  • Chicago has a 6-3 lead over the Pirates in the regular season series between these teams.
  • The total has gone under in six straight games between the Cubs and Pirates.

Pirates vs Cubs Model Projection

Score Projection: Cubs 5 – Pirates 4

Win Probability: Cubs 60%, Pirates 40%

Final Thoughts

The Cubs are much better than the Pirates this season. But an overall advantage in talent might not be enough to overcome the fact that Javier Assad is starting this game for the Cubs. Instead of taking a side in this matchup, I’m more inclined to take the over. Both starting pitchers look vulnerable to getting smacked around in this game and we should see some offensive fireworks.


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Home MLB Picks Pittsburgh Pirates vs Chicago Cubs Prediction – 8/17/2025