Pittsburgh Pirates vs Chicago Cubs Prediction – 8/16/2025

The Chicago Cubs will host the Pittsburgh Pirates at Wrigley Field on Saturday afternoon. Chicago comes in as the clear favorite but they were favored before losing Friday’s series opener as well. The Cubbies will aim to bounce back here and the Pirates will look for their second straight upset win over their division rivals. Here, I have broken down this game and have provided you with my Pirates vs Cubs prediction below.

Our Pirates vs Cubs Pick

  • Pick: Chicago Cubs –1.5
  • Confidence: 4/5
  • Bonus Bets For MLB Saturday: Don’t miss out on our BetMGM bonus code when betting MLB! Click the Claim Bonus button and sign up with code ATSBONUS to get up to $1,500 in bonus bets if your first bet doesn’t win.

Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+
✓ Any Sport Odds Boosts
✓ Free to Play MLB Game
✓ Easy Parlay Builder
Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+
Claim Bonus
Promo Code: ATSBONUS
✓ Any Sport Odds Boosts
✓ Free to Play MLB Game
✓ Easy Parlay Builder
Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+
Claim Bonus
Promo Code: ATSBONUS
Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+

Game Snapshot

  • Matchup: Pittsburgh Pirates vs Chicago Cubs
  • Date & Time: Saturday, August 16, 2025, 2:20 p.m. ET
  • Starting Pitchers: Shōta Imanaga vs Mike Burrows
  • Stadium: Wrigley Field, Chicago, IL
  • Broadcast: Fox Sports 1

Key Storylines

Pitching matchup

Shota Imanaga brings consistency and a sub-4.00 ERA into Saturday’s game. Imanaga has a strong record at home on the season and he will look to prevent the Pirates from stealing a second straight at Wrigley. Mike Burrows has not been as effective as Imanaga this year. Burrows has a 4.66 ERA and his losing record reflects Pittsburgh’s issues both on the mound and at the plate.

Key Players

  • Cubs: Pete Crow-Armstrong and Seiya Suzuki lead the Cubs with 27 home runs. Crow-Armstrong knocked in Suzuki with a hit on Friday.
  • Pirates: Jack Suwinski delivered a ninth-inning game-winning home run on Friday to snap a five-game losing streak for the Pirates. His performance will be something to watch in this contest.

Recent team streaks

  • The Pirates had a five-game losing streak snapped on Friday when they beat the Cubs.
  • The Cubs have lost two games in a row and they have lost four of their last five games.

Best Player Props

PlayerStat TypePick
Pete Crow-ArmstrongHome RunsOver 0.5
Shōta ImanagaStrikeoutsOver 5.5
Nico HoernerTotal BasesOver 1.5
  • The Cubs lead the season series against the Pirates 5-3 after their loss on Friday.
  • Chicago is 31-24 in day games this season.
  • Pittsburgh is 22-30 in their day games in 2025.
  • The Pirates had given up double-digits on the scoreboard in three of their last four games before their 3-2 win on Friday.

Pirates vs Cubs Model Projection

Score Projection: Chicago Cubs 5 – Pittsburgh Pirates 3

Win Probability: Cubs 58%, Pirates 42%

Final Thoughts

This game feels like the perfect spot for the Cubs to bounce back from their disappointing performance in their last outing. The bats of the Cubs should wake up after a sluggish start to this series. Chicago has hit nearly twice as many home runs as Pittsburgh has this season. I expect some power from the Cubs here to even this series at a game apiece going into Sunday’s rubber match.


Affiliate Disclosure ATS.io features affiliate links to licensed online casinos, sportsbooks, and gambling platforms. That means if you click on them and end up signing up or making a deposit, we might earn a commission at no extra cost to you. We only work with licensed and reputable online casinos, social casinos and sportsbooks. Our content whether it’s reviews, guides, or betting tips is written with the goal of being honest, helpful, and based on real experience. While we do earn through affiliate partnerships, it doesn’t affect our recommendations. If a site isn’t safe or doesn’t meet our standards, we won’t promote it. Simple as that. We also take responsible gambling seriously. We encourage all our readers to gamble safely, set limits, and know when to take a break. Have questions? Feel free to reach out. We’re always happy to chat.

̈́

Related Articles

Leave a Comment

Home MLB Picks Pittsburgh Pirates vs Chicago Cubs Prediction – 8/16/2025