New York Yankees vs St. Louis Cardinals Prediction – 8/17/2025
The New York Yankees will conclude their three-game series against the St. Louis Cardinals on Sunday at Busch Stadium. These clubs have split the first two games and both teams are hoping to secure a series win. Before this game begins from Busch Stadium, continue reading to get my analysis and my Yankees vs Cardinals prediction.
Our Yankees vs Cardinals Pick
- Pick: Yankees -1.5
- Confidence: ★★★★☆
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Game Snapshot
- Matchup: New York Yankees vs St. Louis Cardinals
- Date & Time: Sunday, August 17, 2025, 2:15 PM ET
- Starting Pitchers: Will Warren (NYY) vs. Miles Mikolas (STL)
- Stadium: Busch Stadium, St. Louis, MO
- Broadcast: YES Network (NYY), FDSMW (STL)
Key Storylines
Pitching Matchup
Will Warren is 7–5 with 4.34 ERA and will take the mound for the Yankees in this game. He is coming off a solid outing against the Twins. He allowed two earned runs over 6.2 innings in that start. Miles Mikolas is 6–9 with a 4.97 ERA and he will start for the Cardinals. Mikolas has allowed 67 runs in 117 innings pitched and has a 5.06 expected ERA. He could be in for further challenges against a potent Yankees lineup.
Key Players
- Yankees: Ben Rice had seven RBI for the Yankees in their win on Saturday and Rice could be an important part of the Yankees lineup again today.
- Cardinals: The bullpen of the Cardinals will be the key for them in this game. St. Louis gave up 12 runs as a team to the Yankees on Saturday and has to be better to win this game.
Recent Team Streaks
- Yankees: The Yankees have won four of their last five games and have won two straight against the Cardinals in this series.
- Cardinals: The Cardinals are on a four-game losing streak and have dropped two games below .500 for the year.
Best Player Props
| Player | Prop |
|---|---|
| Aaron Judge | Over 0.5 Home Runs |
| Ben Rice | Over 1.5 RBIs |
| Willson Contreras | Over 0.5 Home Runs |
Betting Trends & H2H
- These teams are 1-1 against each other so far this season.
- The over/under is 1-1 in games played by the Yankees and Cardinals this year.
Yankees vs Cardinals Model Projection
- Score Projection: Yankees 6 – Cardinals 4
- Win Probability: Yankees 55%, Cardinals 45%
Final Thoughts
The Yankees enter this game with a more potent offense and a starting pitcher in Will Warren who has been reliable this season. The struggles of Mikolas should continue in this game against one of the most dangerous lineups in baseball. I will lay the runline with the Yankees at plus money in the final game between New York and St. Louis this season.
