The New York Yankees (88-68) will host the Chicago White Sox (58-98) at Yankee Stadium on Tuesday night. With postseason implications still on the line for New York, the Yankees are heavy favorites against the team with the worst record in the American League. Before the action begins in the Bronx, you can continue reading to get my White Sox vs Yankees prediction for this huge matchup for the home team.
Our White Sox vs Yankees Pick
- Pick: Yankees −1.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Chicago White Sox vs New York Yankees
- Date & Time: Tuesday, September 23, 2025, 7:05 PM ET
- Starting Pitchers: Luis Gil vs Shane Smith
- Stadium: Yankee Stadium, Bronx, NY
- Broadcast: YES and CHSN
Key Storylines
- Pitching matchup: Luis Gil has been a strong option for New York on the mound since his return from injury. He is 4-1 and has a 3.33 ERA in his starts. Though his strikeout and walk rates have not been great, he presents a challenge for the White Sox lineup. Shane Smith’s 4.06 ERA suggests more vulnerability, especially against a Yankees lineup capable of capitalizing on mistakes.
- Key Players:
- Aaron Judge for New York has been a terror this season, combining power and consistency. He’s one to watch in any game the Yankees are in, especially as he competes with Seattle’s Cal Raleigh for the AL MVP.
- Lenyn Sosa leads the White Sox and is one of the few bright spots in their struggling offense. He leads his team in batting average, home runs, and RBI.
- Recent team streaks:
- The White Sox have lost two games in a row and they are now 40 games below .500 for the season.
- The Yankees have won two straight games and they are two games back of the Toronto Blue Jays in the AL East standings going into the final week of the regular season.
Best Player Props
| Player | Prop |
|---|---|
| Aaron Judge | 2+ Total Bases |
| Luis Gil | Over 6.5 Strikeouts |
Betting Trends & H2H
- The Yankees hold a 3-1 lead over the White Sox in their season series this year.
- New York is 44-31 at home on the season.
- Chicago is 25-50 on the road this year.
- The Yankees have scored 10 runs in two of their four games against the White Sox this season.
White Sox vs Yankees Model Projection
- Score Projection: Yankees 6 – White Sox 2
- Win Probability: Yankees 66.8%, White Sox 33.2%
Final Thoughts
New York enters this game with clearer incentives, a more reliable starter, and home-field advantage. Chicago’s offense has not shown enough lately to overcome a pitcher of Gil’s caliber, and their pitching has been hit-or-miss away from home. I am going to take the Yankees to win and cover the runline at home in this contest. They should keep the pressure on the Blue Jays in the AL East race by getting a third straight win here.
